Protein Alignment CG12219 and LOC4576343

DIOPT Version :10

• Sequence 1: NP_572312.1
• Gene: CG12219 / 31572
• FlyBaseID: FBgn0043796
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_001237668.2
• Gene: LOC4576343 / 4576343
• VectorBaseID: AGAMI1_006583
• Length: 1044
• Species: Anopheles gambiae
• Alignment Length: 660
• Identity: 138/660 - (20%)
• Similarity: 203/660 - (30%)
• Gaps: 253/660 - (38%)

  Fly    60 DAISTCICTECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDGSETQLDAQP------Q 118
            |.:....|..|.......:|..|.|         :|:.:       |.|...:.|..|      :
Mosquito   452 DVVQKVQCNVCQRWFHGKYNLRKHV---------RFMHL-------EGGQVFRCDLCPHESPNSR 500

  Fly   119 LLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYT 183
            .||:..:...||     .:|.|..|.|.||.:.||:||||:|||.....|..|:..|...:|.|.
Mosquito   501 ALLDHKKRVHVV-----ERFACELCGKRFKRKLYLKEHIASHTGQPLYECGICDAKFNSNANCYN 560

  Fly   184 HVKSKHTTQWLKARE-----ERDAAKS--NQNHTTPEETAPAVLVPVPAPAPALASAPASSASPG 241
            |.||||..:|...|:     :|.|..|  .:...:.||         |.|.........:.|.
Mosquito   561 HRKSKHPEEWQARRQAFFEAQRKAPDSELKKEEISTEE---------PLPEQVCQQCQTTVAE-- 614

  Fly   242 NTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPP-------- 298
              .:..:....|:.......||......|..|:..|...|:..|:|.|.    :.||
Mosquito   615 --FHVYSQQVEANQRQLRLELATDTDVEPEPVKVEPDLQIEIMPAEGME----ELPPGIECVDVK 673

  Fly   299 ---SGS--------------------------RGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQ 334
               .||                          |.:|.|..|::..:.:....:||:..:.:....
Mosquito   674 EEYDGSITAQSESNLDASTDDEYVVATRRKVRRKARERKERKEESAERGKDKSEGNGAARQQEKD 738

  Fly   335 KRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLCASLLQ-----QQH---------- 384
            .|:||..                            :|:..:|:.||.     |:|
Mosquito   739 DRIKEFY----------------------------TLECEICSILLDDFVQLQEHYQLVHDTRGY 775

  Fly   385 ----QEQLFAVMSATAAAAAAVGT-----SSATTTTTTTTGTMMAHPYGNHPPSETDKRP----- 435
                .:|||...:.....|...||     ...|..|.......||..:|..     ::||
Mosquito   776 IRCCNKQLFHRYTLLDHIAVHRGTIRCEVCDRTYKTKRYLALHMAKSHGTE-----EERPFKCDQ 835

  Fly   436 ---AAPLQAVI--------------------------------HAAPVSIICPNCGEL------- 458
               |.|.|.::                                |:...:.||..||::
Mosquito   836 CGLAYPKQYLLRSHQLMHVQAECHVCKKVLSSNYALKVHLTQMHSDDGNQICATCGKIFRTKAAM 900

  Fly   459 -----------------------------------------PGQ------------NHRCLS--- 467
                                                     .||            |.|.||
Mosquito   901 ERHIKEHMGLEPIERMQCEYCQKWFNGKYNLNKHIRFLHNERGQVFRCDLCAHESPNSRALSYHK 965

  Fly   468 -----KPKYACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYHHTKRKHKAEWE 527
                 :.|:.|::|||.||.|.||.||.|:||.|.|:||.:|..:|.|.:|.:.|.|.||..|||
Mosquito   966 QRVHVQEKHECELCGKRFKRKLYLREHIASHTNVPLYTCEYCGMKFNSHANHFTHRKNKHPEEWE 1030

  Fly   528 RSRATRSAAK 537
            ..:..|...|
Mosquito  1031 AHKRMRMLKK 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12219	NP_572312.1	zf-AD	2..91	CDD:214871	6/30 (20%)
		PHA00733	<117..189	CDD:177301	28/77 (36%)
		C2H2 Zn finger	140..160	CDD:275368	11/19 (58%)
		zf-H2C2_2	152..177	CDD:463886	12/24 (50%)
		C2H2 Zn finger	168..186	CDD:275368	6/17 (35%)
		C2H2 Zn finger	473..493	CDD:275370	12/19 (63%)
		C2H2 Zn finger	501..522	CDD:275370	7/20 (35%)
LOC4576343	XP_001237668.2	None