Protein Alignment CG12219 and LOC4576335

DIOPT Version :10

• Sequence 1: NP_572312.1
• Gene: CG12219 / 31572
• FlyBaseID: FBgn0043796
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_001237671.3
• Gene: LOC4576335 / 4576335
• VectorBaseID: AGAMI1_003412
• Length: 548
• Species: Anopheles gambiae
• Alignment Length: 625
• Identity: 125/625 - (20%)
• Similarity: 202/625 - (32%)
• Gaps: 160/625 - (25%)

  Fly     3 CRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTCIC 67
            |||||..|:.|           .|....::|...:.:...:...:.||         :|..:.:|
Mosquito     5 CRLCLARLENQ-----------RSNATIEEEGFREKLKTLFSFPITSI---------EAFPSTVC 49

  Fly    68 TECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDG----SETQLDAQP-------QLLL 121
            .:|.:::..||.:.:.|:..|..|            ||...    .|.:::..|       :|..
Mosquito    50 VQCEARVSDFHTYHEQVKSNQDQL------------WSTQHQKYFEEVKVEPAPDADYDVFELPF 102

  Fly   122 EPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHIATHTGD-RPIACPYCEMAFRCRSNMYT-- 183
            |.||..:.....:....|...|::. ::::..|:.|.:...| ..:...|...:....||..:
Mosquito   103 EEAEPVEGAPKESCKNEPDSKCQQQ-QLQQLDEQTIDSDLDDGMKLEDEYNPPSSSAASNNNSDD 166

  Fly   184 ---HVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVN 245
               .||.:        |.:|....:::..||.....|              .:.|.:.|||....
Mosquito   167 SEYEVKPR--------RSKRVTDTADRTRTTRRGRPP--------------KSEAGTRSPGEQKK 209

  Fly   246 PAATATPASSATPTTNLAAAPLPSPPTVQQL-PLSVIKSQPSEAMNLTIT----------KTPPS 299
            .:........||..||            |:| ....:|.:..|....:.|          :||..
Mosquito   210 KSPIVVRRCQATNETN------------QKLREFYDMKCEMCEEQLESFTALKNHYYRTHRTPGY 262

  Fly   300 GSRGSRNRSSR---------------------RKTHSPKK--VQHTEGSDVSDEDSPQK------ 335
            .....|...||                     .||.|.:.  :.|........||.|.|
Mosquito   263 IKCCGRTFHSRYRLLEHLSYHVGSSMVRCEECNKTFSSRSYLLVHRSRVHGQAEDRPYKCTQCHQ 327

  Fly   336 ------RLKENEL--ILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVM 392
                  .||.:.:  :..|.......:.:|.||..:......:.:..:|.|..::....|.|
Mosquito   328 SYAMECHLKAHIVSHVRVNCTICGKELASALSLRTHMINMHGNRENHICDSCGREFRSRQAF--- 389

  Fly   393 SATAAAAAAVGTSSATTTTTTTTGTMMAHPYGNHPPSETDKRPAAPLQAVIHAAP--------VS 449
              .......:|...|......     :.|.:.|      .||.......::|...        .|
Mosquito   390 --ERHVKLHLGLEVAEQVQCE-----VCHKWLN------SKRALKMHVKLVHMEAGQTFQCDICS 441

  Fly   450 IICPNCGELPGQNHRCLSKPKYACDVCGKSFKMKRYLEEHFAT-HTGVKLHTCAFCPTEFRSKSN 513
            ..|||...|.....|...:.::.|:.|||.||.:.||:||.|. ||...|::|..|...|.|.:|
Mosquito   442 QQCPNSRALANHKQRVHVEERFKCEECGKLFKRQLYLKEHVAALHTRKPLYSCEVCGATFNSNAN 506

  Fly   514 MYHHTKRKHKAEWERSRATRSAAKAGVQEQMQHTNPSQAQ 553
            .|.|.|.||..|||..|..:...:   |||.||....|.:
Mosquito   507 KYSHRKNKHPVEWEERRKQQLQQQ---QEQQQHHQQQQQE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12219	NP_572312.1	zf-AD	2..91	CDD:214871	18/87 (21%)
		PHA00733	<117..189	CDD:177301	15/84 (18%)
		C2H2 Zn finger	140..160	CDD:275368	3/19 (16%)
		zf-H2C2_2	152..177	CDD:463886	4/25 (16%)
		C2H2 Zn finger	168..186	CDD:275368	3/22 (14%)
		C2H2 Zn finger	473..493	CDD:275370	11/20 (55%)
		C2H2 Zn finger	501..522	CDD:275370	8/20 (40%)
LOC4576335	XP_001237671.3	None