Protein Alignment CG12219 and LOC4576334

DIOPT Version :10

• Sequence 1: NP_572312.1
• Gene: CG12219 / 31572
• FlyBaseID: FBgn0043796
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_001237670.3
• Gene: LOC4576334 / 4576334
• VectorBaseID: AGAMI1_008131
• Length: 524
• Species: Anopheles gambiae
• Alignment Length: 660
• Identity: 125/660 - (18%)
• Similarity: 186/660 - (28%)
• Gaps: 288/660 - (43%)

  Fly     3 CRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTCIC 67
            |||||..:             ||...|...:|:..||       |..:..:.....:..:...:|
Mosquito     5 CRLCLKKI-------------GARKGASITDDEFGAM-------LSRVFTFPVAVTESVLLVNVC 49

  Fly    68 TECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDGSETQLDAQPQLLLEPAEEPKVVT- 131
            .:|...:.:|:.|.:.||..|..|.|:.:.         :....:||..|...:|..|..:.::
Mosquito    50 AKCALMVRNFNAFSEEVEANQNVLLSELMV---------EQKGRKLDDVPHGTVEKEEHTQAISS 105

  Fly   132 --PTTANKFPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWL 194
              ||...|            .|.:|:....|:..:|:.
Mosquito   106 REPTVEPK------------GREVEDVKHDHSLTKPVL--------------------------- 131

  Fly   195 KAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNPAATATPASSATPT 259
                       :|...|.|:          .|...||.....:||
Mosquito   132 -----------DQESETNEK----------KPVEKLADDDDGTAS-------------------- 155

  Fly   260 TNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPPSGSRGSRNRSSRRKTHSPKKVQHTEG 324
                           .||:        |.|.:.:.:..........|.|:   ||
Mosquito   156 ---------------MLPI--------EDMEVLLKEQLDDDFSTDDNNST---TH---------- 184

  Fly   325 SDVSDEDSPQKR-----LKENELILANYNAVAAAVVAAASLTGNPPGQPD-------SLQQ---- 373
               :|:.:|..|     |.||:.|:..:..:...:.         |.|.|       :||:
Mosquito   185 ---TDDKAPNSRSKKPDLHENDRIIMEFFEMRCELC---------PKQADQSFDRFYTLQRHYRV 237

  Fly   374 --------RLCASLLQ---------QQHQEQLFA------------VMSATAAAAAAVGTSSATT 409
                    |.|...|.         |.|:..:..            :|...|....|.|.|.|..
Mosquito   238 AHQCRGFLRCCGRKLYRRFRVMEHIQSHRGTIRCGICDKPFKSKSYLMRHNAEQHVAEGPSFACQ 302

  Fly   410 TTTTTTGTMMAHPYGNH-PPSET----------DKRPAAPLQAVIHAAP---------------- 447
            ....|..|.  .....| |..||          :.|......|:||...
Mosquito   303 HCERTFHTQ--RQLNQHLPAHETTVCKICGKTVNVRYLKQHTALIHGTVRQGYMCDLCGKNFSSS 365

  Fly   448 ----------------VSIICPNCG-ELPG----QNH-RCL---SKPKYACDV------------ 475
                            ..:.||:|| :|.|    |.| ||:   :...|.|:|
Mosquito   366 LALDRHIKQHQGIETIEKLDCPHCGKQLNGKYNLQKHVRCMHVEAGKSYRCEVCGHFSPNSVALE 430

  Fly   476 ----------------CGKSFKMKRYLEEHFAT-HTGVKLHTCAFCPTEFRSKSNMYHHTKRKHK 523
                            |||.||.|.||.||.|. ||...|:.|.||...|:|::|.|.|.|.:|:
Mosquito   431 NHKKRVHTGEHFECGECGKRFKQKIYLTEHVAALHTRKPLYACEFCEATFKSRANYYTHRKTRHR 495

  Fly   524 AEWERSRATR 533
            ||||..|..|
Mosquito   496 AEWEALREER 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12219	NP_572312.1	zf-AD	2..91	CDD:214871	19/87 (22%)
		PHA00733	<117..189	CDD:177301	10/74 (14%)
		C2H2 Zn finger	140..160	CDD:275368	2/19 (11%)
		zf-H2C2_2	152..177	CDD:463886	3/24 (13%)
		C2H2 Zn finger	168..186	CDD:275368	0/17 (0%)
		C2H2 Zn finger	473..493	CDD:275370	13/48 (27%)
		C2H2 Zn finger	501..522	CDD:275370	9/20 (45%)
LOC4576334	XP_001237670.3	None