Protein Alignment CG12219 and pzg

DIOPT Version :10

• Sequence 1: NP_572312.1
• Gene: CG12219 / 31572
• FlyBaseID: FBgn0043796
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_649297.1
• Gene: pzg / 40351
• FlyBaseID: FBgn0259785
• Length: 996
• Species: Drosophila melanogaster
• Alignment Length: 737
• Identity: 135/737 - (18%)
• Similarity: 225/737 - (30%)
• Gaps: 269/737 - (36%)

  Fly    22 AGGASA-------PAPDDEDDG----------------KAMPESYLVQLISIH--------LYLC 55
            ||||||       .|.:|.:.|                :..|::.|..:.:.|        |...
  Fly    51 AGGASAVGGVAQQQAVNDAESGGVGIGGLATRCYICDDRCEPQTSLTDMCTTHTSTKFPNKLAQL 115

  Fly    56 LSRDDAISTC----ICTECCSQLESFHNFWKLVELKQTTLCS---QFLAIDCDV----------- 102
            :.....:..|    :|:.|.:.:..:......||..:|.|.|   :..||:.|:
  Fly   116 VGEGFLVIVCGEDYVCSRCTNLVNYYDRLENDVERVKTNLISLLNKKYAINEDMGQEGSPPLKMQ 180

  Fly   103 -------NWSEDGSETQLDAQPQLLLE--PAEEPKVVTPTTANK--------------------- 137
                   |.|.:.|.:....:|:.||:  |..:.|:...||.:.
  Fly   181 KMVGGSANRSLEESPSADLLRPRKLLQGNPVGQSKIAPGTTQSSVQGTQTVQRKATKIYKCTSCD 245

  Fly   138 --------------------FPCMFCEKSFKMRRYLEEH-IATHTGDRPIACPYCEMAFRCRSNM 181
                                |.|..|.|.|.....:::| :..|.......|..|.:.|...:::
  Fly   246 YKTSDMRLFNTHYETCKQQTFQCKTCRKIFPHFGAMKQHMVRDHNTAMDNTCAMCHINFVNENSL 310

  Fly   182 YTHVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNP 246
            ..|:::.|.|..|               .|...|.||...||     |.|:|.|::|:..|.|..
  Fly   311 RKHMETNHATNVL---------------VTSTTTIPASAAPV-----AAAAAAAAAAANENLVGT 355

  Fly   247 AATATPASSATPTTNLA--------AAPLPSP----------PTVQQLPLSVIKSQPS----EAM 289
            :...........|..:.        ||..|.|          .|.:...:...:.|.:    ...
  Fly   356 SLYTCNHCQFKSTDKVVFDEHMRKHAAGKPKPFKCRLCSQRFETREAATVHAKQHQTNFFKCGTC 420

  Fly   290 NLTITKTPPSGSRGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQKRLKE--NELILANYNAVAA 352
            ::|..|..........::|....|.|||:       .||...:.||.|:|  :|.:..:..|..|
  Fly   421 SMTFPKREMLVKHFEVHQSPSASTVSPKQ-------SVSQNLNTQKLLQETIDEALSDSLPASTA 478

  Fly   353 AVV--------------------------------------------------AAASLTGNPPGQ 367
            |||                                                  ||.:|..:.||:
  Fly   479 AVVATTESENNIRFFSCSICSLTFIQETYYNHHMETHRRDKKATSAGATALNSAATALLSDEPGE 543

  Fly   368 ------PDSLQQRLCA---SLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGT------ 417
                  .:|.:|...|   ||.::.|.::      ..:..|...|:.......|:..|:
  Fly   544 ATGKAGDESGEQNAEADIESLFEKLHSDK------NESGEAPKPGSKGGEMVITSQEGSGGITFN 602

  Fly   418 -MMAHPYGNHPPSETDK-RPAAPLQAVIHAAPVSIICPNCGELPGQNHRCLSKPKYACDVCGKSF 480
             .:..|.|:.  |:.|. ...||:.       |||..||..:...:     |:.:.:.|..|:|.
  Fly   603 ITIPQPDGDQ--SQKDSPNTTAPVS-------VSIDMPNLDQAEDE-----SQSQGSIDAKGESG 653

  Fly   481 KMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSN-------MYHHTKRKHKAEWERSRATRSAAKA 538
            :                       .:...||||       ..........||.|.|..|::|:||
  Fly   654 E-----------------------ASSADSKSNAAPVSMPSLDDDNEAAAAEAEASEETKTASKA 695

  Fly   539 GVQEQMQHTNPSQAQAQPGPAA 560
            | ||:.:......|:::...||
  Fly   696 G-QEKAKAKAGESAKSKEAAAA 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12219	NP_572312.1	zf-AD	2..91	CDD:214871	19/103 (18%)
		PHA00733	<117..189	CDD:177301	18/115 (16%)
		C2H2 Zn finger	140..160	CDD:275368	5/20 (25%)
		zf-H2C2_2	152..177	CDD:463886	5/25 (20%)
		C2H2 Zn finger	168..186	CDD:275368	4/17 (24%)
		C2H2 Zn finger	473..493	CDD:275370	3/19 (16%)
		C2H2 Zn finger	501..522	CDD:275370	4/27 (15%)
pzg	NP_649297.1	C2H2 Zn finger	241..263	CDD:275371	0/21 (0%)
		C2H2 Zn finger	268..289	CDD:275371	5/20 (25%)
		C2H2 Zn finger	297..318	CDD:275371	4/20 (20%)
		C2H2 Zn finger	360..380	CDD:275368	1/19 (5%)
		zf-H2C2_2	373..399	CDD:463886	4/25 (16%)
		C2H2 Zn finger	390..410	CDD:275368	1/19 (5%)
		C2H2 Zn finger	417..437	CDD:275368	2/19 (11%)