DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12219 and CG10654

DIOPT Version :9

Sequence 1:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_001261767.1 Gene:CG10654 / 39428 FlyBaseID:FBgn0036294 Length:412 Species:Drosophila melanogaster


Alignment Length:602 Identity:96/602 - (15%)
Similarity:136/602 - (22%) Gaps:343/602 - (56%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MICRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRD------ 59
            ||||.||..|..|.|           ....|.|.|            ::...|.|...|      
  Fly    38 MICRACLVLLGPQDA-----------CHNLDSEQD------------LASKYYGCTGEDAVRDLP 79

  Fly    60 -DAISTCICTECCSQL-ESFHNFWKLV--ELKQTTLCSQFLAIDC----DVNW------SEDGSE 110
             ..:...|| |||.|| :.||:|.::.  .|:......|.:.|.|    |..|      ||....
  Fly    80 PQLVLKSIC-ECCYQLVQKFHDFQRMCAESLRNFEKLLQDIDIGCHKLEDHTWHDLDTPSESNES 143

  Fly   111 TQLDAQ-----------------PQLLLEPA-------------EEPKVVTPTTANK-------- 137
            |..:||                 ||:.|..|             ||..|:...:|.:        
  Fly   144 TNPEAQSHAPCIAATQEIVSFIWPQVCLPLAVILSRITLGASLEEEVYVIEDESAKQDLGQEKLS 208

  Fly   138 -----------------FPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYTHV 185
                             ..|..|.:.|.....||.|:..|.|.||..|.:|..::...:.:.:|:
  Fly   209 ISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAHMQQHEGLRPYTCVHCAKSYARANLLESHL 273

  Fly   186 KSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNPAATA 250
            :..|        ...|||:              ::...|                  :.|...||
  Fly   274 RQMH--------NNADAAR--------------IIYACP------------------SCNKVYTA 298

  Fly   251 TPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPPSGSRGSRNRSSR---RK 312
                                                                   |||.:   |:
  Fly   299 -------------------------------------------------------NRSLKYHMRR 308

  Fly   313 THSPKKVQHTEGSDVSDEDSPQKRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLCA 377
            ||                    :|..|:|                         .||:       
  Fly   309 TH--------------------ERYHESE-------------------------SPDA------- 321

  Fly   378 SLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGTMMAHPYGNHPPSETDKRPAAPLQAV 442
                                                                             
  Fly   322 ----------------------------------------------------------------- 321

  Fly   443 IHAAPVSIICPNCGELPGQNHRCLSKPKYACDVCGKSFKMKRYLEEHFATHTGV--KLHTCAFCP 505
                                       ::.|:.|||.|..|.:|..|...|..|  :.:.|..|.
  Fly   322 ---------------------------RHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCD 359

  Fly   506 TEFRSKSNMYHHTKRKH 522
            ..|.:|.||..|..|||
  Fly   360 RRFYTKENMVDHLLRKH 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12219NP_572312.1 zf-AD 2..94 CDD:285071 25/101 (25%)
C2H2 Zn finger 140..160 CDD:275368 6/19 (32%)
COG4049 149..204 CDD:226535 13/54 (24%)
C2H2 Zn finger 168..186 CDD:275368 3/17 (18%)
C2H2 Zn finger 473..493 CDD:275370 8/19 (42%)
C2H2 Zn finger 501..522 CDD:275370 8/20 (40%)
CG10654NP_001261767.1 zf-AD 39..115 CDD:285071 25/99 (25%)
C2H2 Zn finger 228..248 CDD:275368 6/19 (32%)
C2H2 Zn finger 256..313 CDD:275368 17/171 (10%)
C2H2 Zn finger 289..314 CDD:275368 11/117 (9%)
zf-C2H2 323..345 CDD:278523 8/21 (38%)
C2H2 Zn finger 325..345 CDD:275368 8/19 (42%)
C2H2 Zn finger 355..376 CDD:275368 8/20 (40%)
C2H2 Zn finger 385..405 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45455479
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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