DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12219 and CG8388

DIOPT Version :10

Sequence 1:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_611075.1 Gene:CG8388 / 36763 FlyBaseID:FBgn0034062 Length:572 Species:Drosophila melanogaster


Alignment Length:656 Identity:132/656 - (20%)
Similarity:194/656 - (29%) Gaps:250/656 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MICRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTC 65
            |.|.||...:|        |.||.....:.:.:..|       |..:|..|.:|.:. |...:..
  Fly     1 MPCFLCTQTVD--------DAAGNIEFASEEADSLG-------LRCIIEKHFWLQIP-DSKRAGY 49

  Fly    66 ICTECCSQLESFHNFWKLVE-----LKQTTLCS-------------------------------- 93
            :|..|..||..||||:..||     |:||.|..                                
  Fly    50 VCGPCWEQLLLFHNFYLNVEQAHKALEQTVLKETSPPEVVASALEEHIVKSEHDDSVAAAVKRRR 114

  Fly    94 -----------------------------QFLAIDCDV-NWSEDGSETQLDAQPQLLLEPAEEPK 128
                                         :|...|..: :..||..|........:..|.||:|:
  Fly   115 GRPRKVAQQDAREELKSVLEQINLNEIKIEFPEADLTIADVLEDQEEQDFLPDDCISKEGAEDPE 179

  Fly   129 VV---TPTTANKF---------------PCMFC----EKSFKMRRYLEEHIATHTGDRPIACPYC 171
            |:   .||...|.               |...|    :||.:...|:.||.       .:.|..|
  Fly   180 VLEKKPPTLKRKVSGRSRGRRRVQLAERPNTSCLPKIQKSQEFNDYIREHY-------KVQCHIC 237

  Fly   172 EMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSN------QNHTTPEETAPAVLVPVPAPAPAL 230
            .:.....|.|..||:.:|..:.......|...|..      :.|..||....::...|.....:|
  Fly   238 NLPMEDFSEMLAHVRREHKQRGYAMCCNRKFLKRGVLVDHLRRHQDPETFKCSICGRVMGHRRSL 302

  Fly   231 ASAPASSASPGNTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKS--------QPSE 287
            .                                          ..:.:..|||        |.|:
  Fly   303 E------------------------------------------LHMRMHEIKSRGRLYRCEQCSK 325

  Fly   288 AMNLTITKTPPSGSRGSRNRSSRRK-THSPK---KVQHTEGSDVSDEDSPQKRLKENELILANYN 348
            |....:.             ..|.| ||.|:   ||..|.    .::..|.:...:..:.|.:.|
  Fly   326 AFYSAVV-------------YERHKLTHIPREQWKVPCTH----CEKTYPSQYTMQQHVKLVHLN 373

  Fly   349 AVAAAV-VAAASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTT 412
            ..|... |...|:.|.     ::|.:.:      ::|          |....||:......:..|
  Fly   374 LYAKICDVCGKSIRGR-----EALARHM------EEH----------TGGPQAAIKCHLCDSMLT 417

  Fly   413 TTTG----TMMAHPYGNHPPSETD---KRPAAPLQAVIHAAPVSIICPNCGELPGQNHRCLSKPK 470
            |..|    ..|.|...|..|.:.:   |                 |||:   |....|..    |
  Fly   418 TKYGLARHIKMMHTAENLQPMQCEFCLK-----------------ICPS---LQAHQHHI----K 458

  Fly   471 YA--------CDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYHHTKRKHKAEWE 527
            |.        |.:|.|:||....|:||..||||..|:||..||..|.|.:||:.|.|:.|:.|||
  Fly   459 YTHNTARSHQCPMCEKAFKRPNELKEHMTTHTGEVLYTCPHCPQTFNSNANMHAHRKKVHRKEWE 523

  Fly   528 RSRATR 533
            .:|..|
  Fly   524 ENRHKR 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12219NP_572312.1 zf-AD 2..91 CDD:214871 26/93 (28%)
PHA00733 <117..189 CDD:177301 21/93 (23%)
C2H2 Zn finger 140..160 CDD:275368 6/23 (26%)
zf-H2C2_2 152..177 CDD:463886 5/24 (21%)
C2H2 Zn finger 168..186 CDD:275368 5/17 (29%)
C2H2 Zn finger 473..493 CDD:275370 8/19 (42%)
C2H2 Zn finger 501..522 CDD:275370 9/20 (45%)
CG8388NP_611075.1 zf-AD 3..78 CDD:462262 24/90 (27%)
C2H2 Zn finger 264..281 CDD:275368 2/16 (13%)
C2H2 Zn finger 289..309 CDD:275368 2/61 (3%)
C2H2 Zn finger 320..340 CDD:275368 5/32 (16%)
C2H2 Zn finger 350..369 CDD:275368 2/22 (9%)
C2H2 Zn finger 440..461 CDD:275368 8/44 (18%)
C2H2 Zn finger 469..489 CDD:275368 8/19 (42%)
C2H2 Zn finger 497..515 CDD:275368 8/17 (47%)

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