DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12219 and az2

DIOPT Version :9

Sequence 1:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster


Alignment Length:529 Identity:105/529 - (19%)
Similarity:153/529 - (28%) Gaps:192/529 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 EHI---ATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTT----- 211
            ||.   ..|..|    | |.||.|:.......|||           |..:|..|.|...|     
  Fly    14 EHFVLACAHQND----C-YVEMEFKRWREFIVHVK-----------EHLEANPSMQQELTTSEVI 62

  Fly   212 -----PEETAPA-VLVPVPAPAPALAS------APAS----SASPGNTVNPAATATPASSATPTT 260
                 .||.:|| |.:....|...||.      .|:|    |.||............:||.|...
  Fly    63 SSAKCEEEVSPAKVFIVEEPPENCLAEDMFVDVPPSSENDESTSPVEEEEEEDDEVDSSSMTVDC 127

  Fly   261 NLAA------APLP---------SPPTVQQLPL-------------------------SVIKSQP 285
            .|..      |||.         ||...|.:.|                         ..:..|.
  Fly   128 ELGTRNSTHFAPLTKFNPTFYRRSPRITQFIELYKQQTCLWDPADESYRDKEKRANAYEELLEQL 192

  Fly   286 SEAMNLTIT-----KTPPSGSRGSRNRSSRRKTHSPKKVQ--------------HTEGSDVSDED 331
            ...:||.:|     |...|......:.|.::||....||.              ..|.:|..|.|
  Fly   193 KATVNLHLTAYKLKKCITSLHAQYASISRQKKTQKLTKVPLYYHGKYSFLAERGSLEDADSDDVD 257

  Fly   332 SPQKRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLC------ASLLQ--------- 381
            ...|    .:|:....|.:....:   .|....|...|...:..|      :||::         
  Fly   258 GDGK----IKLVFTEENQLTTQFI---DLYSKFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEF 315

  Fly   382 -------------QQHQEQLFAVMSATAAAAAAVGTSSATTT----------------------- 410
                         .|...|.::....|......||.|.|...                       
  Fly   316 SLGLVTHYDVYDSIQSMRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNSFMPTKSFRQKLKCEVC 380

  Fly   411 --TTTTTGTMMAHPYGNHPPSE------------TDKRPAAPLQAVIHAAPV----SIICPNCGE 457
              :.:|...:.||.:.:|...:            .|::  ..||.  |:..|    |.:|..|..
  Fly   381 EHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRK--CHLQQ--HSQRVHMDKSFVCEICSR 441

  Fly   458 ---------LPGQNH--RCLSKPKYACDVCGKSFKMKRYLEEHF-ATHTGVKLHTCAFCPTEFRS 510
                     :..:.|  :.::|| :.|:.|||.||.|..:..|. |.||.::...|..||.:|.:
  Fly   442 SFAFGNQLAIHKRTHDEKHVAKP-FVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFLT 505

  Fly   511 KSNMYHHTK 519
            |.::..|.|
  Fly   506 KRDLKDHVK 514

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12219NP_572312.1 zf-AD 2..94 CDD:285071
C2H2 Zn finger 140..160 CDD:275368 2/7 (29%)
COG4049 149..204 CDD:226535 14/51 (27%)
C2H2 Zn finger 168..186 CDD:275368 6/17 (35%)
C2H2 Zn finger 473..493 CDD:275370 9/20 (45%)
C2H2 Zn finger 501..522 CDD:275370 7/19 (37%)
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:287510 12/84 (14%)
GT1 276..>341 CDD:304916 8/67 (12%)
C2H2 Zn finger 377..398 CDD:275368 3/20 (15%)
C2H2 Zn finger 408..429 CDD:275368 4/24 (17%)
C2H2 Zn finger 436..456 CDD:275368 2/19 (11%)
C2H2 Zn finger 467..488 CDD:275368 9/20 (45%)
C2H2 Zn finger 496..516 CDD:275368 7/19 (37%)
C2H2 Zn finger 524..544 CDD:275368
C2H2 Zn finger 551..572 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45439988
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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