DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12219 and CG8944

DIOPT Version :9

Sequence 1:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster


Alignment Length:526 Identity:81/526 - (15%)
Similarity:133/526 - (25%) Gaps:267/526 - (50%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 ISTCICTECCSQLESFHNFWKLVELKQTTLCSQFLA----IDCDVNWSEDGSETQLDAQPQLLLE 122
            ::|...::..|||...::..|:..|....|..:|:|    .| .:::.:|      |..|   .:
  Fly   421 VTTIQISKRISQLRFDYSKQKMERLNSERLGKKFIANYLYYD-QMHFMDD------DIPP---FK 475

  Fly   123 PAEEPKVV-------------TPTTANKFPCMFCEKSFKMRRYLEEHIATHTG---DRPIACPYC 171
            .|..|::|             .|:....:.|..|...|...:..:.|...|.|   :....|..|
  Fly   476 CAHCPEIVQTLRELDLHMLTHQPSLGGGYYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELC 540

  Fly   172 EMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPAS 236
            ..:||.::|...|::..:...:|                                          
  Fly   541 TASFREKANYDEHLRRHNEELFL------------------------------------------ 563

  Fly   237 SASPGNTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITK------ 295
                                                            ||.|:|.:|.:      
  Fly   564 ------------------------------------------------PSLALNHSIMEGGLGDD 580

  Fly   296 ---TPPSGSRGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQKRLKENELILANYNAVAAAVVAA 357
               .....||||.:|..||  |:.|..     .|:.|:|.                         
  Fly   581 EIGVEGEESRGSGSRRKRR--HAAKAT-----DDMVDDDD------------------------- 613

  Fly   358 ASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGTMMAHP 422
             .:.|...|                                    |:...        ||.:|.|
  Fly   614 -RIGGGGGG------------------------------------GSGGG--------GTDIAKP 633

  Fly   423 YGNHPPSETDKRPAAPLQAVIHAAPVSIICPNCGELPG-----------QNHRC----------- 465
            ||                        ..:|......||           :..||           
  Fly   634 YG------------------------CDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKS 674

  Fly   466 --------------LSKPKYACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYH 516
                          .|..::.||:|||:||..:.|:.|...|..:|.:.|..|.:.|...:.:|.
  Fly   675 FVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYL 739

  Fly   517 HTKRKH 522
            | ||:|
  Fly   740 H-KRRH 744

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12219NP_572312.1 zf-AD 2..94 CDD:285071 7/31 (23%)
C2H2 Zn finger 140..160 CDD:275368 4/19 (21%)
COG4049 149..204 CDD:226535 10/57 (18%)
C2H2 Zn finger 168..186 CDD:275368 6/17 (35%)
C2H2 Zn finger 473..493 CDD:275370 9/19 (47%)
C2H2 Zn finger 501..522 CDD:275370 7/20 (35%)
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:287510
MADF 379..472 CDD:214738 12/57 (21%)
C2H2 Zn finger 476..496 CDD:275368 3/19 (16%)
C2H2 Zn finger 506..526 CDD:275368 4/19 (21%)
C2H2 Zn finger 537..557 CDD:275368 6/19 (32%)
C2H2 Zn finger 636..656 CDD:275368 3/19 (16%)
zf-C2H2_8 639..712 CDD:292531 14/72 (19%)
C2H2 Zn finger 666..688 CDD:275368 0/21 (0%)
zf-C2H2 694..716 CDD:278523 9/21 (43%)
C2H2 Zn finger 696..716 CDD:275368 9/19 (47%)
zf-H2C2_2 708..733 CDD:290200 7/24 (29%)
C2H2 Zn finger 724..744 CDD:275368 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45455478
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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