Protein Alignment CG12219 and CG11696

DIOPT Version :10

• Sequence 1: NP_572312.1
• Gene: CG12219 / 31572
• FlyBaseID: FBgn0043796
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_572731.1
• Gene: CG11696 / 32104
• FlyBaseID: FBgn0030314
• Length: 664
• Species: Drosophila melanogaster
• Alignment Length: 742
• Identity: 151/742 - (20%)
• Similarity: 223/742 - (30%)
• Gaps: 301/742 - (40%)

  Fly     1 MICRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTC 65
            |||||||.  |.:..|.:|........||           ...|.:||..||.|.|:.:|.:|||
  Fly     1 MICRLCLE--DAEHGVPIFGQEPPMGQPA-----------HRQLAELIERHLLLVLAENDVVSTC 52

  Fly    66 ICTECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDGSETQLDAQPQLLLEPAEEPKVV 130
            :|..|..||.....|..:|..||.:| .:.|.:           :|:|...|: |.||  ||.:|
  Fly    53 LCNRCWRQLAEIEQFCSMVAEKQRSL-HRSLQL-----------KTELPELPE-LTEP--EPALV 102

  Fly   131 TPTTANKFPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWLK 195
            ...|.:..                |...::.||                ::..|:..:.....|.
  Fly   103 VWNTESPI----------------EPKLSYEGD----------------DIKDHILCEPVIDALS 135

  Fly   196 AREERDAAKSN------QNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNPAATATPAS 254
            |.:|:|:...:      :..:.|:|...      |.|.|               |.|.....|..
  Fly   136 AGDEKDSDYGDTFEPDFEPESQPDEEEE------PEPDP---------------VKPRPRGRPRK 179

  Fly   255 SATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPPSGSRGSRNRSSRRKTHSPKKV 319
            :|...|:                 .:||.:..:.......|......|.||.|....|..|....
  Fly   180 TALQQTH-----------------QIIKRKYEKRKQQNKAKITELSLRESRARQRELKRSSAGAE 227

  Fly   320 QHTEG-------SDVSDEDSP-----------QKRLKENELILANYN------------------ 348
            ...:|       .||..|.:|           :.|.|..:|:.|:.|
  Fly   228 DDQDGDEDEEDEEDVGGELTPDADEQPKPRGKRGRPKTKKLVTADDNDDTSEVPVKRSSIKEMDD 292

  Fly   349 AVAAAVVAAASLTGNPPGQPDSLQQRL-------------------------------------C 376
            .:||.|....::...|....:.|::..                                     |
  Fly   293 YIAANVKLDCAICAAPLEDFNDLKRHFRVEHDCTGYVKCCNNRYKKRTLYVDHLHCHKDPQYFSC 357

  Fly   377 AS--------------LLQQQHQEQLFAVMSATAAAAAA------------VGTS-----SATTT 410
            .|              :|:...|:|......|...|..|            .||.     ...:.
  Fly   358 QSCRKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKGTERPEVCDTCSK 422

  Fly   411 TTTTTGTMMAHPYGNHPPSETDKRPAAPLQAVIHAAPVS-IICPNCG------------------ 456
            |..|...:.||.          ||        :|||..: |||..||
  Fly   423 TFRTKFELSAHV----------KR--------MHAADFTPIICDICGTHFRSKANFLIHKKALHP 469

  Fly   457 ---------ELPGQ----------------------NHRCL--------------------SKPK 470
                     .|.|:                      .:|||                    |..:
  Fly   470 DGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDTKYRCLLCNAEKSSRAALSSHMRYHHSAKR 534

  Fly   471 YACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYHHTKRKHKAEWERSRATRSA 535
            :.|.:|.|.||:.|.|.||.|||||:.|:.|.||...|:|.:||::|.|:.|..:|.|..:..|:
  Fly   535 HKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTRTFKSHANMHNHKKKMHPNDWVRKYSQPSS 599

  Fly   536 AKAGVQEQMQHTN-PSQAQAQPGPAAA 561
            :.......:.|.| |:    ||.|.||
  Fly   600 SITSTAAPLAHPNHPN----QPAPPAA 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12219	NP_572312.1	zf-AD	2..91	CDD:214871	30/88 (34%)
		PHA00733	<117..189	CDD:177301	12/71 (17%)
		C2H2 Zn finger	140..160	CDD:275368	1/19 (5%)
		zf-H2C2_2	152..177	CDD:463886	3/24 (13%)
		C2H2 Zn finger	168..186	CDD:275368	1/17 (6%)
		C2H2 Zn finger	473..493	CDD:275370	10/19 (53%)
		C2H2 Zn finger	501..522	CDD:275370	9/20 (45%)
CG11696	NP_572731.1	zf-AD	2..81	CDD:462262	31/92 (34%)
		C2H2 Zn finger	332..349	CDD:275368	0/16 (0%)
		C2H2 Zn finger	357..378	CDD:275368	3/20 (15%)
		C2H2 Zn finger	388..408	CDD:275368	3/19 (16%)
		C2H2 Zn finger	417..438	CDD:275368	6/38 (16%)
		C2H2 Zn finger	447..465	CDD:275368	3/17 (18%)
		C2H2 Zn finger	478..498	CDD:275368	2/19 (11%)
		C2H2 Zn finger	509..529	CDD:275368	2/19 (11%)
		zf-H2C2_2	521..545	CDD:463886	4/23 (17%)
		C2H2 Zn finger	537..557	CDD:275368	10/19 (53%)
		C2H2 Zn finger	565..583	CDD:275368	8/17 (47%)