Protein Alignment CG3815 and phf12b

DIOPT Version :9

• Sequence 1: NP_572311.1
• Gene: CG3815 / 31571
• FlyBaseID: FBgn0029861
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_002664670.2
• Gene: phf12b / 325296
• ZFINID: ZDB-GENE-110628-2
• Length: 942
• Species: Danio rerio
• Alignment Length: 1018
• Identity: 298/1018 - (29%)
• Similarity: 430/1018 - (42%)
• Gaps: 285/1018 - (27%)

  Fly     3 KLDQDPNASLSIMEQIKQLIRPPPNED-EKMMQRSTNTKHPYYRRPGRGHNHDYCDACEEGGNLL 66
            |:..|.:.|..:||||:||:.||.:|| ||..:....|     ||.||..|||.||:|.|||:||
Zfish     9 KILYDLDTSGGLMEQIQQLLAPPRSEDGEKRRKPERET-----RRGGRATNHDTCDSCREGGDLL 68

  Fly    67 CCDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSC--------------------RMSKLSQPPASS 111
            |||.||::|||||.:||||.|.:|.|.|:||.|                    ::||.|..||:.
Zfish    69 CCDHCPAAFHLQCCNPPLSREMLPPGDWMCHRCSVRKKKREQKAEQVNGALERQLSKRSSSPAAE 133

  Fly   112 SKASS--VERVPSAGSG-----------------SRANTPSSGDLESIPLKIRNLRKRSNSERNS 157
            .:..:  ::.:|||.||                 ||..||:|......|         :.||.|.
Zfish   134 LELGTLRLDGLPSAASGGLRLAVAQVRLLERRTSSRPGTPTSNASTDTP---------TPSEHND 189

  Fly   158 TEKLLAKMPMSIQRALDPNKKP---TPLDDVIRAATMMNPQQFSLPPELELHTQFPGNGKVQPVQ 219
            .::.|..:...:|.:...|..|   .|...:|.||...||.||.||.||...|..||:.|.:..:
Zfish   190 VDEDLMDVEEDVQGSESENATPRLKKPFQMLIAAAMERNPTQFQLPSELTCTTSLPGSSKRRRKE 254

  Fly   220 QTHPPSGNGGNRRCAGNQRRNSKPFELDAQGLVPLPAKTCFYCTRSCKRAPLISCDYCPLYFHQD 284
            :.           ...|.:|  ...|||..||||||.|.||.|.:||:.||||.||||.|.||.|
Zfish   255 EA-----------IGKNMKR--PQHELDPSGLVPLPVKVCFTCGKSCRVAPLIQCDYCALLFHMD 306

  Fly   285 CLDPPLTALPAGLWMCPNHAENFIDANMTNSISATERVRLWNRFHQPLDHENVKLEFFRRVNTRN 349
            ||||||||:|.|.||||||.|:.: .|..| ::.:.|.::::.|...|....||::|.|.|:.::
Zfish   307 CLDPPLTAMPTGRWMCPNHVEHMV-LNQKN-VTLSTRCQVFDHFQDRLSQHAVKVDFLRWVHRQH 369

  Fly   350 PPFRTKRNLRARAHI-----EVPAIVRYHYDHPPPLLPSMRQTLRYDRVKRRN------------ 397
            .|     |.|...||     :||..::.||.:||.|:         |:|..||
Zfish   370 HP-----NRRGVRHIKKKTLKVPNAIKSHYQNPPLLM---------DQVGLRNGELVPNGFMEQE 420

  Fly   398 ------NLPTEVEE-----------------ISRESVTESLLKDLEALRTAHAKFREIQ------ 433
                  :|.:|.|:                 :|.:.::.| |:|.|....:.||.:|..
Zfish   421 CSSSTQHLTSEEEQEEWLRHVIALQCSIMKHLSAKQMSSS-LRDSEQADLSDAKTQECMEMQELS 484

  Fly   434 -------------------REFGTL---------ETAIDGDSDSDPSPEEKRTETNTPADKVNGE 470
                               :...|:         |.:..|::|   ||.||.|..|.|   |..|
Zfish   485 SQDSDYLQSRSTKVGPQGAQVLSTIVPKHPESCNEQSSQGEAD---SPTEKGTGVNGP---VACE 543

  Fly   471 VDT-------ENPNTESNAQASEQ--PSVVKVESKTSLEVEASFEEDEEDSKKSTGIID------ 520
            .||       ..|::.|..|..|.  |:.|.:::::|....:..:.|    ..||.::.
Zfish   544 GDTCTTAETSHKPSSPSRRQNLESALPNHVDIKTESSSPFSSCMQRD----SPSTSLLSGSPARH 604

  Fly   521 --ADLLHLDVDIIKKLAHQRLQQLVEEHPEIVTQYKNRTAARRLRQLASVDGTHVAGETAALQGQ 583
              :.|.:....:...|:.|..:..|.  |::::..|..|....:..|.|.....|.|:|..
Zfish   605 HGSTLGNSSSGLNSSLSSQTKENKVS--PDLMSAGKGSTLPSSIGSLYSYIKNVVQGDTEV---- 663

  Fly   584 LAPEDMNRFS-----LLFTSETSSILAQKNGNAADEDPATALHPALATAAAIAAADAAAESYAPR 643
                |||:..     ||.......:|:.|:..|:.:   ....||           |.|....|.
Zfish   664 ----DMNKLDEELIRLLAWQRIQQLLSPKSLQASSK---CGTPPA-----------ATASLSKPS 710

  Fly   644 ARSDTEKAYELASRLELKLLQCKVQARAVITPLGDMLEDSRWFSSLGLDHSIFMRYRTLYIGYGG 708
            ..:|.:|.              .||||||:.||            .|...:|.|.|||||||.|.
Zfish   711 LHADAQKR--------------DVQARAVLCPL------------TGKGAAINMCYRTLYIGTGA 749

  Fly   709 HYSPSTTLAQTETVDLSAIGYCCRISPQHAIIFYDEFSKSYELINYSEFGTEVNGQLYACDVTER 773
            ...          |.|:..|:|..:|.:||.|||||.:|.|||:||||.||.|:..||:||.::
Zfish   750 EMD----------VCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSD- 803

  Fly   774 MTTHAGKPMRPDDAELKKRVDEMLDKRRNINRQFETKKIDKERLAPIVKPA-------------- 824
                  ||.....:.|..:|...:  |.|.:|    :.|.:....|:..|.
Zfish   804 ------KPNITSPSALASKVQNSI--RGNKSR----RPIGEVSTEPVPVPTDSMMSSLAQGGPKN 856

  Fly   825 -CRCMNAGPVPMVDGA---WEGSAVLAHGSLLRFGCLSFVFVV 863
             |.| .|....::.|:   |||:|:|.|.|.::.|||.|:|.:
Zfish   857 PCNC-KASSSSLIGGSGAGWEGTALLHHSSCIKVGCLQFLFSI 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3815	NP_572311.1	PHD1_PHF12	55..99	CDD:277008	28/43 (65%)
		BAH	75..198	CDD:295389	46/164 (28%)
		PHF12_MRG_bd	175..211	CDD:293342	15/38 (39%)
		PHD2_PHF12_Rco1	259..303	CDD:277009	31/43 (72%)
		FHA	<732..>765	CDD:238017	19/32 (59%)
phf12b	XP_002664670.2	PHD1_PHF12	57..101	CDD:277008	28/43 (65%)
		BAH	77..>141	CDD:322012	21/63 (33%)
		PHF12_MRG_bd	210..248	CDD:318859	16/37 (43%)
		PHD2_PHF12_Rco1	280..325	CDD:277009	31/44 (70%)
		FHA	<741..>796	CDD:238017	30/64 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586356
Domainoid	1	1.000	122	1.000	Domainoid score	I5585
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2356
OMA	1	1.010	-	-		QHG49783
OrthoDB	1	1.010	-	-		D1203363at2759
OrthoFinder	1	1.000	-	-		FOG0003315
OrthoInspector	1	1.000	-	-		otm25870
orthoMCL	1	0.900	-	-		OOG6_106762
Panther	1	1.100	-	-	O	PTHR46309
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2689
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.000