DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3815 and cph1

DIOPT Version :9

Sequence 1:	NP_572311.1	Gene:	CG3815 / 31571	FlyBaseID:	FBgn0029861	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_593079.1	Gene:	cph1 / 2542318	PomBaseID:	SPAC16C9.05	Length:	404	Species:	Schizosaccharomyces pombe

Alignment Length:	300	Identity:	69/300 - (23%)
Similarity:	102/300 - (34%)	Gaps:	108/300 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DQDPNASLSIMEQIKQLIRPPPNEDEKMMQRSTNTKH---------PYYRRPGRG--HNHDYCDA 58
            |::.:.|..:.:|........||:......|.::.|.         |..||..:.  .|.|||.|
pombe    58 DKEMDISSPVKKQKASYSNKSPNKAPIQKSRGSSLKSHLETESQQTPVKRRRRKATIRNVDYCSA 122

  Fly    59 CEEGGNLLCCDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSCRMSKLSQPPASSSKASSVERVPSA 123
            |...|..:||:.||.||||.|.:|||:.|:||.|.|.|.:|.: |...||
pombe   123 CGGRGLFICCEGCPCSFHLSCLEPPLTPENIPEGSWFCVTCSI-KSHHPP--------------- 171

  Fly   124 GSGSRANTPSSGDLESIPLKIRNLRKRSNSERNSTEKLLAKMPMSIQRALDPNKKPTPLDDVIRA 188
                                                    |.|:||.         :.|.|.|.:
pombe   172 ----------------------------------------KHPLSIW---------SQLYDWIDS 187

  Fly   189 ATMMNPQQFSLPPELELHTQFPGNGKVQPVQQTHPPSGNGGNRRCAGNQRRNSKPFELDAQGLVP 253
               .||.|:.||.:| :| .|.|..:          ...|..:...|         |:|......
pombe   188 ---QNPSQYRLPDDL-VH-YFHGISR----------GDTGAYKETEG---------EMDTDEFSA 228

  Fly   254 LPAKT-------CFYCTRSCKRAPLI-SCDYCPLYFHQDC 285
            ||..:       |.||::....|..: .|..|..::|::|
pombe   229 LPTGSSITNLAYCGYCSKPSMGACWVYGCQLCDTFYHKNC 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3815	NP_572311.1	PHD1_PHF12	55..99	CDD:277008	23/43 (53%)
		BAH	75..198	CDD:295389	27/122 (22%)
		PHF12_MRG_bd	175..211	CDD:293342	11/35 (31%)
		PHD2_PHF12_Rco1	259..303	CDD:277009	7/27 (26%)
		FHA	<732..>765	CDD:238017
cph1	NP_593079.1	PHD1_Rco1	119..163	CDD:277010	23/43 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4299
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003315
OrthoInspector	1	1.000	-	-		otm47342
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1691
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930