Protein Alignment CG3815 and aire

DIOPT Version :10

• Sequence 1: NP_572311.1
• Gene: CG3815 / 31571
• FlyBaseID: FBgn0029861
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_012826738.3
• Gene: aire / 106557435
• XenbaseID: XB-GENE-6461262
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 293
• Identity: 73/293 - (24%)
• Similarity: 112/293 - (38%)
• Gaps: 54/293 - (18%)

  Fly    15 MEQIKQLIRPPPNEDEKMMQR-------------STNTKHPYYRRPGRGHNHDYCDACEEGGNLL 66
            ||:..:.:...|....|:..|             |...:.|.|:     .|.|.|..|.:||.|:
 Frog   216 MERELEAVEKNPTHPLKLTLRPKLISQQVGSIALSVPAELPQYQ-----SNDDECSVCRDGGELI 275

  Fly    67 CCDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSCRMSK-LSQPPASSSKASSVERVPSAGSGSRAN 130
            |||.||.||||.|..|||:.  ||||.|.|.:|...: :|.......:.:.:.:.||..|....:
 Frog   276 CCDGCPRSFHLSCLVPPLTH--IPSGTWRCDTCNTGRPMSDGQPEMGETTGLSKKPSQESAETQS 338

  Fly   131 TPSSGDLESIPLKIRNLRKRSNSERNSTEKLLAKMPMSIQRALDPNKKPTPLDDVIRAATMMNPQ 195
            .......|.:..|..::.::|||.:|.....:...|     .:.|  |||       |.|....|
 Frog   339 QKRMKVCEMLADKHDSIIQKSNSIQNQIYPQIVAQP-----EICP--KPT-------ARTQTCSQ 389

  Fly   196 Q---FSLPPELELHTQFPGNGKVQPVQQTHPPSGNGGNRRCAGNQRRNSKPFELDAQGL-VPLPA 256
            |   :..||:.:...|     .:..:..:..|.....::....:..|.|...:.::|.| :|.|.
 Frog   390 QQSSYQAPPQPQACPQ-----SLSSLCMSQTPLRQFCSQLVPRSHIRTSHQLQTNSQHLSIPQPC 449

  Fly   257 KTCFYCTRSCKRAPLISCDYCPLYFHQDCLDPP 289
            .|         ..|.|.|....|. .|:|..||
 Frog   450 ST---------SGPQIPCTTLTLQ-SQNCPTPP 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3815	NP_572311.1	PHD1_PHF12	55..99	CDD:277008	24/43 (56%)
		BAH	75..198	CDD:470629	33/126 (26%)
		PHF12_MRG_bd	175..211	CDD:465250	11/38 (29%)
		PHD2_PHF12_Rco1	259..303	CDD:277009	8/31 (26%)
		FHA	667..861	CDD:469597
aire	XP_012826738.3	HSR	11..103	CDD:460835
		PHD1_AIRE	264..306	CDD:277014	24/43 (56%)