Protein Alignment wuho and Wdr4

DIOPT Version :10

• Sequence 1: NP_572307.1
• Gene: wuho / 31566
• FlyBaseID: FBgn0029857
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001385973.1
• Gene: Wdr4 / 690032
• RGDID: 1585179
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 110/408 - (26%)
• Similarity: 183/408 - (44%)
• Gaps: 77/408 - (18%)

  Fly    46 TSQSQESCTAAAAASTATAASGQAPGGKEQQLANQPEEGGTSASASGLGCATSTSVQNVAYSPDG 110
            |:.|.:.|..:...|||...|.|...|::    .||.:.|            |.::....:|..|
  Rat    27 TASSDDDCLFSYDCSTAEKKSVQEDKGED----GQPADRG------------SDTILASTFSKSG 75

  Fly   111 QLLAVTTSGKQKALLLYRSRPENARLLSARPLARASSALRFCSDSSSILVTDKTGDCYQYDCVEV 175
            :..|:|...|:  |:|:|::|  .:.||.|.:.|..:||.|.:....:||.||:||.|.:..::.
  Rat    76 RYFALTDDSKR--LILFRTKP--WQCLSVRTVVRRCTALTFTASEDRVLVADKSGDVYSFPVLDS 136

  Fly   176 EAPPRLLLGHLSVVYDILWSEDQQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLTE 240
            ....||.|||||::.|:..|.|.|.::|.|||:||||:...|...|.::||||.||||.:.::..
  Rat   137 GGCGRLELGHLSMLLDVAVSPDDQFVLTADRDEKIRVSWAAAPHSIEAFCLGHTEFVSRIFVVPS 201

  Fly   241 --QHIASASGDKTLRVWNYIQGKELLQHELPA---PAVRLLVRQLEPEKVF-----QAAVLFYEH 295
              :.:.|:|||.|||:|.|..|.:|...:|.:   |....:.:.|...::.     ...||..|.
  Rat   202 HPELLLSSSGDGTLRLWKYRSGCQLQCCDLASLQEPGEHSVHKGLAASRIAFWGRESYVVLLCEC 266

  Fly   296 VDALGLYRLERSSDD------------TWSVTATQLVCAEAGSWSISNFTLTSDRIYITGAENER 348
            |....:::|:.|...            .|.|...:    ..|.|.:.:            ..:..
  Rat   267 VPVGFVFQLDASRQQLVFRQRLTFPHRVWDVVFEE----TRGLWVLQD------------CRDAP 315

  Fly   349 LSL---------RVYDIATGQPASSGVPEGWLKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNV 404
            |:|         ...|.|..|...|.:.|.|  .:|:|....::|        ....:|..|||:
  Rat   316 LALWRPMGSEWQAAPDDAVSQRLCSHLRESW--AMLEGSAGADDG--------FRSLYKATFDNM 370

  Fly   405 SDYLERKKRRIEEQQQQK 422
            :.||::|:.|:::|.::|
  Rat   371 TSYLKKKEERLKQQLKKK 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wuho	NP_572307.1	WD40	<98..274	CDD:441893	66/180 (37%)
		WD40 repeat	101..142	CDD:293791	12/40 (30%)
		WD40 repeat	147..184	CDD:293791	12/36 (33%)
		WD40 repeat	189..220	CDD:293791	13/30 (43%)
		WD40 repeat	233..267	CDD:293791	12/35 (34%)
Wdr4	NP_001385973.1	WD40	<51..218	CDD:441893	64/186 (34%)
		WD40 repeat	67..104	CDD:293791	12/40 (30%)
		WD40 repeat	107..143	CDD:293791	11/35 (31%)
		WD40 repeat	151..186	CDD:293791	14/34 (41%)