Protein Alignment wuho and Wdr4

DIOPT Version :9

• Sequence 1: NP_572307.1
• Gene: wuho / 31566
• FlyBaseID: FBgn0029857
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: XP_008771050.1
• Gene: Wdr4 / 690032
• RGDID: 1585179
• Length: 455
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 110/408 - (26%)
• Similarity: 183/408 - (44%)
• Gaps: 77/408 - (18%)

  Fly    46 TSQSQESCTAAAAASTATAASGQAPGGKEQQLANQPEEGGTSASASGLGCATSTSVQNVAYSPDG 110
            |:.|.:.|..:...|||...|.|...|::    .||.:.|            |.::....:|..|
  Rat    70 TASSDDDCLFSYDCSTAEKKSVQEDKGED----GQPADRG------------SDTILASTFSKSG 118

  Fly   111 QLLAVTTSGKQKALLLYRSRPENARLLSARPLARASSALRFCSDSSSILVTDKTGDCYQYDCVEV 175
            :..|:|...|:  |:|:|::|  .:.||.|.:.|..:||.|.:....:||.||:||.|.:..::.
  Rat   119 RYFALTDDSKR--LILFRTKP--WQCLSVRTVVRRCTALTFTASEDRVLVADKSGDVYSFPVLDS 179

  Fly   176 EAPPRLLLGHLSVVYDILWSEDQQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLTE 240
            ....||.|||||::.|:..|.|.|.::|.|||:||||:...|...|.::||||.||||.:.::..
  Rat   180 GGCGRLELGHLSMLLDVAVSPDDQFVLTADRDEKIRVSWAAAPHSIEAFCLGHTEFVSRIFVVPS 244

  Fly   241 --QHIASASGDKTLRVWNYIQGKELLQHELPA---PAVRLLVRQLEPEKVF-----QAAVLFYEH 295
              :.:.|:|||.|||:|.|..|.:|...:|.:   |....:.:.|...::.     ...||..|.
  Rat   245 HPELLLSSSGDGTLRLWKYRSGCQLQCCDLASLQEPGEHSVHKGLAASRIAFWGRESYVVLLCEC 309

  Fly   296 VDALGLYRLERSSDD------------TWSVTATQLVCAEAGSWSISNFTLTSDRIYITGAENER 348
            |....:::|:.|...            .|.|...:    ..|.|.:.:            ..:..
  Rat   310 VPVGFVFQLDASRQQLVFRQRLTFPHRVWDVVFEE----TRGLWVLQD------------CRDAP 358

  Fly   349 LSL---------RVYDIATGQPASSGVPEGWLKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNV 404
            |:|         ...|.|..|...|.:.|.|  .:|:|....::|        ....:|..|||:
  Rat   359 LALWRPMGSEWQAAPDDAVSQRLCSHLRESW--AMLEGSAGADDG--------FRSLYKATFDNM 413

  Fly   405 SDYLERKKRRIEEQQQQK 422
            :.||::|:.|:::|.::|
  Rat   414 TSYLKKKEERLKQQLKKK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wuho	NP_572307.1	WD40 repeat	101..142	CDD:293791	12/40 (30%)
		WD40	104..361	CDD:295369	80/287 (28%)
		WD40	<107..>266	CDD:225201	63/160 (39%)
		WD40 repeat	147..184	CDD:293791	12/36 (33%)
		WD40 repeat	189..220	CDD:293791	13/30 (43%)
		WD40 repeat	233..267	CDD:293791	12/35 (34%)
Wdr4	XP_008771050.1	WD40	60..>272	CDD:295369	76/221 (34%)
		WD40	<72..340	CDD:225201	85/287 (30%)
		WD40 repeat	110..147	CDD:293791	12/40 (30%)
		WD40 repeat	150..186	CDD:293791	11/35 (31%)
		WD40 repeat	194..229	CDD:293791	14/34 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3914
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4583
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D399439at33208
OrthoFinder	1	1.000	-	-		FOG0004300
OrthoInspector	1	1.000	-	-		oto98288
orthoMCL	1	0.900	-	-		OOG6_103715
Panther	1	1.100	-	-	LDO	PTHR16288
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3033
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800