DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and ZFAND4

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	XP_016872420.1	Gene:	ZFAND4 / 93550	HGNCID:	23504	Length:	741	Species:	Homo sapiens

Alignment Length:	277	Identity:	56/277 - (20%)
Similarity:	94/277 - (33%)	Gaps:	101/277 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KAKIQDKEENPPEHQRLIFGGKHLENGRTLSDYNIQKESTIYLVLRLRGGMQIFVKTLTGKTITL 91
            |.|:.|..:.||                   .:|.......|..|.....|::|::||||....|
Human    53 KVKVMDNRKEPP-------------------FFNDDNMGPFYYRLHFCDTMELFIETLTGTCFEL 98

  Fly    92 EVEPSDTIENVKAKIQDKEENPPEHQRLIFGGKHLENGRTLSDYNIQKESTIYLVLRLRGGMQIF 156
            .|.|.:|:.:|||||:..|  .|....|....::|::.|                      ::::
Human    99 RVSPFETVISVKAKIRRLE--VPTDDPLRKMAEYLDSSR----------------------VEVW 139

  Fly   157 VKTLTGKTITLEVEP---------------------SDSIENVKARIH--DKEGIPPDQQRLIF- 197
            .||...|.:|..|..                     |||.:.:...:|  .::|    :.|:.:
Human   140 EKTSCSKQVTFLVYQEGDQLNFFPAVDRGDGTLTPLSDSSKKIDFHLHVLRRKG----EHRMSYC 200

  Fly   198 ---AGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLT----------GKTITLEVEPSD 249
               :|..:.:..|..|...:..|:         |.||...::|          .|.:.|..:|.
Human   201 FLCSGGSMYNSDTDEDEETEPSSS---------GQQIIENSITMNKMKLLKAKMKNMNLSKKPK- 255

  Fly   250 TIKHVKARIHDKDGIPP 266
              |.||.:.|     ||
Human   256 --KAVKIKPH-----PP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398	8/48 (17%)
		UBQ	1..72	CDD:214563	7/44 (16%)
		Ubiquitin	77..152	CDD:176398	20/74 (27%)
		UBQ	77..148	CDD:214563	20/70 (29%)
		Ubiquitin	153..228	CDD:176398	15/101 (15%)
		UBQ	153..224	CDD:214563	15/97 (15%)
		UBQ	229..296	CDD:214563	12/48 (25%)
		UBQ	229..296	CDD:294102	12/48 (25%)
ZFAND4	XP_016872420.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810