DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and isg15

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001191098.1	Gene:	isg15 / 558956	ZFINID:	ZDB-GENE-021211-1	Length:	157	Species:	Danio rerio

Alignment Length:	162	Identity:	62/162 - (38%)
Similarity:	89/162 - (54%)	Gaps:	15/162 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEENPPEHQRLIFGGKHLENG---------RTL 132
            ||:.||.|.|....|||....|:..:|..|......|...|:|     ..|||         |||
Zfish     1 MQLTVKLLGGDVKRLEVSGDATVGILKQVISQYFNVPTFKQKL-----SAENGQRISLEDESRTL 60

  Fly   133 SDYNIQKESTIYLVLRLR-GGMQIFVKTLTGKTITLEVEPSDSIENVKARIHDKEGIPPDQQRLI 196
            |.|.:..:|.:.|::... |..|:|||...|:..|.:|:.:::::.::.:|:.||.:|.||||||
Zfish    61 SSYGLNSDSVVMLLITTNPGTFQVFVKNEKGQVKTYDVDANETVDQLQTKIYQKERVPKDQQRLI 125

  Fly   197 FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG 228
            |.|:|||.|..|.||:|...||:|:.||||||
Zfish   126 FKGRQLESGMKLQDYDITSLSTIHMTLRLRGG 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398
		UBQ	1..72	CDD:214563
		Ubiquitin	77..152	CDD:176398	25/84 (30%)
		UBQ	77..148	CDD:214563	25/79 (32%)
		Ubiquitin	153..228	CDD:176398	34/74 (46%)
		UBQ	153..224	CDD:214563	30/70 (43%)
		UBQ	229..296	CDD:214563	62/162 (38%)
		UBQ	229..296	CDD:294102	62/162 (38%)
isg15	NP_001191098.1	UBQ	1..76	CDD:214563	25/79 (32%)
		UBQ	3..75	CDD:294102	23/76 (30%)
		UBQ	82..153	CDD:214563	30/70 (43%)
		UBQ	83..157	CDD:294102	34/73 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810