DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and Rad23

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001259052.1	Gene:	Rad23 / 43785	FlyBaseID:	FBgn0026777	Length:	414	Species:	Drosophila melanogaster

Alignment Length:	242	Identity:	60/242 - (24%)
Similarity:	98/242 - (40%)	Gaps:	53/242 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEENPPEH----QRLIFGGKHLENGRTLSDYNI 61
            |.|.:|.|..:|.|:|..|..|:..:|.||  .||..||:    |:||:.|..|.:.||:..||:
  Fly     1 MIITIKNLQQQTFTIEFAPEKTVLELKKKI--FEERGPEYVAEKQKLIYAGVILTDDRTVGSYNV 63

  Fly    62 QKESTIYLVLRLRGGM----QIFVKTLTGKTITLEVE-------------PSDTIENVKAKIQDK 109
            .::..|.::|......    |:.||.....|.|.:.:             ||.|  |.:..:..:
  Fly    64 DEKKFIVVMLTRDSSSSNRNQLSVKESNKLTSTDDSKQSMPCEEANHTNSPSST--NTEDSVLSR 126

  Fly   110 EENPPEHQRLIFGGKHLENGRTLSDYNIQKESTIYLVLRLRGGMQIFVKTLTGKTITLEVE---P 171
            |..|.....||  |:       |:..::|..:...|::    |.:.      .:|:...||   |
  Fly   127 ETRPLSSDELI--GE-------LAQASLQSRAESNLLM----GDEY------NQTVLSMVEMGYP 172

  Fly   172 SDSIENVKARIHDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKEST 218
            .:.:|...|..::.   |......:..|...|:|   :.||...|||
  Fly   173 REQVERAMAASYNN---PERAVEYLINGIPAEEG---TFYNRLNEST 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398	27/78 (35%)
		UBQ	1..72	CDD:214563	26/74 (35%)
		Ubiquitin	77..152	CDD:176398	17/91 (19%)
		UBQ	77..148	CDD:214563	17/87 (20%)
		Ubiquitin	153..228	CDD:176398	15/69 (22%)
		UBQ	153..224	CDD:214563	15/69 (22%)
		UBQ	229..296	CDD:214563
		UBQ	229..296	CDD:294102
Rad23	NP_001259052.1	rad23	1..413	CDD:273167	60/242 (25%)
		RAD23_N	1..76	CDD:176400	27/76 (36%)
		UBA1_Rhp23p_like	153..199	CDD:270561	10/58 (17%)
		XPC-binding	242..296	CDD:286376
		UBA2_HR23A	371..411	CDD:270610
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900