DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and UBQLN2

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_038472.2	Gene:	UBQLN2 / 29978	HGNCID:	12509	Length:	624	Species:	Homo sapiens

Alignment Length:	72	Identity:	25/72 - (34%)
Similarity:	37/72 - (51%)	Gaps:	1/72 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 MQIFVKTLTGKTITLEVEPSDSIENVKARIHDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKES 217
            :::.|||...|. ...|..:.|::..|..|..:.....||..||||||.|:|..||..:.|....
Human    33 IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGL 96

  Fly   218 TLHLVLR 224
            |:|||::
Human    97 TVHLVIK 103

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398
		UBQ	1..72	CDD:214563
		Ubiquitin	77..152	CDD:176398
		UBQ	77..148	CDD:214563
		Ubiquitin	153..228	CDD:176398	25/72 (35%)
		UBQ	153..224	CDD:214563	25/70 (36%)
		UBQ	229..296	CDD:214563
		UBQ	229..296	CDD:294102
UBQLN2	NP_038472.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		UBQ	33..103	CDD:214563	25/70 (36%)
		hPLIC_N	33..103	CDD:176403	25/70 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	106..141
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	287..349
		STI1	382..426	CDD:128966
		12 X 3 AA tandem repeats of P-X-X	491..526
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	512..556
		UBA_PLICs	581..620	CDD:270582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900