DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and rhp23

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_596231.1	Gene:	rhp23 / 2540481	PomBaseID:	SPBC2D10.12	Length:	368	Species:	Schizosaccharomyces pombe

Alignment Length:	238	Identity:	48/238 - (20%)
Similarity:	90/238 - (37%)	Gaps:	48/238 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 MQIFVKTLTGKTITLEVEPSDT-IENVKAKIQDKEENPPEHQRLIFGGKHLENGRTLSDYNIQKE 140
            |.:..|.|..:...:....:|| |..:|.|||.::....|.|:||:.|:.|.:.:|:.:|||::
pombe     1 MNLTFKNLQQQKFVISDVSADTKISELKEKIQTQQNYEVERQKLIYSGRILADDKTVGEYNIKE- 64

  Fly   141 STIYLVLRLRGGMQIFVKTLTGKTITLEVEPSDSIE---NVKARIHDKEGIPPDQ---------Q 193
                         |.|:..:..:..|....|..:..   |..|.:.:|:...|..         |
pombe    65 -------------QDFIVCMVSRPKTSTSTPKSAASPAPNPPASVPEKKVEAPSSTVAESTSTTQ 116

  Fly   194 RLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIKHVKARI 258
            .:..|.....|....|:..|...:     |.:.....:.|:.:    :.:..|.|:..:.::|..
pombe   117 TVAAAAPSNPDTTATSEAPIDANT-----LAVGAQRNVAVENM----VEMGYERSEVERAMRAAF 172

  Fly   259 HDKD--------GIPPDHQRLIFAGKQLEDGRTLSDYNIQKES 293
            ::.|        |||.|    |...::.|....|:....|.|:
pombe   173 NNPDRAVEYLLTGIPED----ILNRQREESAAALAAQQQQSEA 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398
		UBQ	1..72	CDD:214563
		Ubiquitin	77..152	CDD:176398	20/75 (27%)
		UBQ	77..148	CDD:214563	20/71 (28%)
		Ubiquitin	153..228	CDD:176398	14/86 (16%)
		UBQ	153..224	CDD:214563	13/82 (16%)
		UBQ	229..296	CDD:214563	14/73 (19%)
		UBQ	229..296	CDD:294102	14/73 (19%)
rhp23	NP_596231.1	rad23	1..363	CDD:273167	48/238 (20%)
		RAD23_N	1..76	CDD:176400	22/88 (25%)
		UBA1_Rhp23p_like	141..187	CDD:270561	7/49 (14%)
		XPC-binding	247..302	CDD:286376
		UBA2_Rhp23p_like	321..360	CDD:270564
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900