DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11700 and UBD

DIOPT Version :9

Sequence 1:	NP_572306.1	Gene:	CG11700 / 31564	FlyBaseID:	FBgn0029856	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_006389.2	Gene:	UBD / 10537	HGNCID:	18795	Length:	165	Species:	Homo sapiens

Alignment Length:	156	Identity:	52/156 - (33%)
Similarity:	84/156 - (53%)	Gaps:	6/156 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 IFVKTLTGKTITLEVEPSDTIENVKAKIQDKEENPPEHQRLIFGGKHLENGRTLSDYNIQKESTI 143
            :.|::.....:|.:..|.|:::.:|..::.|.:.|.:.|.|:.|.|.|:..|:||.|.|.||.||
Human    10 VHVRSEEWDLMTFDANPYDSVKKIKEHVRSKTKVPVQDQVLLLGSKILKPRRSLSSYGIDKEKTI 74

  Fly   144 YLVLRL----RGGMQIFVKTL--TGKTITLEVEPSDSIENVKARIHDKEGIPPDQQRLIFAGKQL 202
            :|.|::    ...:.:|:...  ..|...|:|..|.|:..|||.|..|.||.|:.|.:...||:|
Human    75 HLTLKVVKPSDEELPLFLVESGDEAKRHLLQVRRSSSVAQVKAMIETKTGIIPETQIVTCNGKRL 139

  Fly   203 EDGRTLSDYNIQKESTLHLVLRLRGG 228
            |||:.::||.|:|.:.|.|.....||
Human   140 EDGKMMADYGIRKGNLLFLACYCIGG 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11700	NP_572306.1	Ubiquitin	1..76	CDD:176398
		UBQ	1..72	CDD:214563
		Ubiquitin	77..152	CDD:176398	23/76 (30%)
		UBQ	77..148	CDD:214563	22/68 (32%)
		Ubiquitin	153..228	CDD:176398	27/76 (36%)
		UBQ	153..224	CDD:214563	27/72 (38%)
		UBQ	229..296	CDD:214563	52/156 (33%)
		UBQ	229..296	CDD:294102	52/156 (33%)
UBD	NP_006389.2	UBQ	8..79	CDD:214563	22/68 (32%)
UBD	NP_006389.2	UBQ	104..165	CDD:320785	25/60 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54325
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820