DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3781 and Atxn3

DIOPT Version :9

Sequence 1:	NP_572303.4	Gene:	CG3781 / 31560	FlyBaseID:	FBgn0029853	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	XP_006240547.1	Gene:	Atxn3 / 60331	RGDID:	621567	Length:	382	Species:	Rattus norvegicus

Alignment Length:	220	Identity:	56/220 - (25%)
Similarity:	82/220 - (37%)	Gaps:	74/220 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IYHERQTRHLCGLHALNNLFQGPDMFSKSEL----------------------DDYCTTL----- 76
            |:||:|...||..|.||||.|| :.||..||                      :||.|.|
  Rat     4 IFHEKQEGSLCAQHCLNNLLQG-EYFSPVELSSIAHQLDEEERLRMAEGGVTSEDYRTFLQQPSG 67

  Fly    77 -----------TPRNWLNPHR-SWIGWG-----NYDVNVIMYALQQRNCEAVWFDR------RRD 118
                       :|.:...|.| |.:..|     .....||..||:....|.:.|:.      |.|
  Rat    68 NMDDSGFFSIQSPYSLAFPPRTSLVHLGRPSGPELRAEVISNALKVWGLELILFNSPEYQRLRID 132

  Fly   119 PHCLNLSVIFGFILNVPAQMSLGYYIPLPFHMRHWLALRRLNGSYYNLDSKLREPKCLGTEQQFL 183
            |  :|..   .||.|               :..||..:|:|...::||:|.|..|:.:  ...:|
  Rat   133 P--INER---SFICN---------------YKEHWFTVRKLGKQWFNLNSLLTGPELI--SDTYL 175

  Fly   184 EFLATQLQMD-HELFLVLDEETDCK 207
            .....|||.: :.:|:|..:..||:
  Rat   176 ALFLAQLQQEGYSIFVVKGDLPDCE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3781	NP_572303.4	Josephin	44..184	CDD:280299	45/189 (24%)
Atxn3	XP_006240547.1	Josephin	9..190	CDD:280299	49/203 (24%)
Atxn3	XP_006240547.1	SUIM_assoc	291..348	CDD:293225
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1482722at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920