Protein Alignment Spx and pabpc1l

DIOPT Version :10

• Sequence 1: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001005062.1
• Gene: pabpc1l / 448615
• XenbaseID: XB-GENE-5742459
• Length: 629
• Species: Xenopus tropicalis
• Alignment Length: 487
• Identity: 110/487 - (22%)
• Similarity: 162/487 - (33%)
• Gaps: 189/487 - (38%)

  Fly    13 ATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMI 77
            |::|.|.|...|:|.:|:|.|..|||::::.:.:|..|:...||.::.|....||:..:..||..
 Frog    11 ASLYVGDLHPDVTEAMLYEKFSPAGPIMSIRVCRDIATRRSLGYAYINFQQPADAERALDTMNFE 75

  Fly    78 KLYGKPIRV--NKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQ------------ 128
            .:.|:|||:  ::.....:...|| |:||.|||..:|.|.|||||||||.||.
 Frog    76 VIKGRPIRIMWSQRDPGLRKSGVG-NVFIKNLDESIDNKALYDTFSAFGNILSCKVVCDEHGSRG 139

  Fly   129 ----------------------------------------------------------------- 128
                                                                             
 Frog   140 YGFVHFETQEAANRAIQTMNGMLLNDRKVFVGHFKSRRERELEYGAKVMEFTNVYIKNFGEDMDD 204

  Fly   129 --------------TPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFK 179
                          :.|:|.| :||:|:.|.|:|:.:.|.:..|:..|||:.:..|.|.|..|.|
 Frog   205 KRLREIFSAFGNTLSVKVMMD-DTGRSRGFGFVNYGNHEEAQKAVSEMNGKEVNGRMIYVGRAQK 268

  Fly   180 KDHKGERHGS--------AAERLLAAQNPSTHA---------DR------PHQLFADAPVQT--- 218
            :.   ||.|.        ..||:...|..:.:.         ||      |:.....|.|.|
 Frog   269 RI---ERQGELKRKFEQIKQERINRYQGVNLYVKNLDDGIDDDRLRKEFSPYGTITSAKVMTEGG 330

  Fly   219 ------------------MMPQMPGQIPAQMP-----------------GQMMP--PPMMAPPPP 246
                              .:.:|.|:|.:..|                 .|.|.  ..|.|.|.|
 Frog   331 HSKGFGFVCFSSPEEATKAVTEMNGRIVSTKPLYVALAQRKEERKAILTNQYMQRLATMRAMPGP 395

  Fly   247 VVPVSNNNMGMLAPP-----PPVPQPAPFPATIPPPPLPPMTGG-------------QPPLPPAM 293
            :       :|....|     |.:||| |......|.|:.|:...             |||.|...
 Frog   396 L-------LGSFQQPANYFLPAMPQP-PNRTFYSPNPVAPVRQAPQWTSHQSRPPQYQPPAPLMR 452

  Fly   294 GIPPPPRMMQPNAWAPPGMPAPPPRPPPTNWR 325
            .:  |||.|..|...........||..|.:.|
 Frog   453 AV--PPRRMSSNISTMKQASTQVPRVAPHSQR 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	24/74 (32%)
		RRM2_SF3B4	99..181	CDD:409772	39/172 (23%)
pabpc1l	NP_001005062.1	PABP-1234	11..612	CDD:130689	110/487 (23%)