Protein Alignment Spx and sap-49

DIOPT Version :10

• Sequence 1: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001379265.1
• Gene: sap-49 / 4363023
• WormBaseID: WBGene00004723
• Length: 388
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 229/388 - (59%)
• Similarity: 263/388 - (67%)
• Gaps: 60/388 - (15%)

  Fly     1 MAAGPIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEE 65
            |:||||.|||||||||.||||:||||::||||.|||||||:|:|||||||..|||:|||||:.||
 Worm     1 MSAGPIVERNQDATIYVGGLDEKVSESILWELMVQAGPVVSVNMPKDRVTANHQGFGFVEFMGEE 65

  Fly    66 DADYGIKIMNMIKLYGKPIRVNKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQTP 130
            ||||.|||:||||||||||:|||||||:||:|||||||:||||.|||||||||||||||||||.|
 Worm    66 DADYAIKILNMIKLYGKPIKVNKASAHEKNMDVGANIFVGNLDPEVDEKLLYDTFSAFGVILQVP 130

  Fly   131 KIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFKKDHKGERHGSAAERLL 195
            |||||.::|.||.|||||||||||||.|::|||||:||||.|:||||||:|.||||||:||||:|
 Worm   131 KIMRDVDSGTSKGFAFINFASFEASDTALEAMNGQFLCNRAITVSYAFKRDSKGERHGTAAERML 195

  Fly   196 AAQNPSTHADRPHQLFADAPVQTMMPQMPGQIPAQMPG-------------QMMPPPMMA----- 242
            |||||....|||||:|:|.|:     .:|...|..|||             ...|||:|.
 Worm   196 AAQNPLFPKDRPHQVFSDVPL-----GVPANTPLAMPGVHAAIAAHATGRPGYQPPPLMGMAQSG 255

  Fly   243 ---------PPPPVV----PVSNNNMGMLAPPPPVPQPAPFPATIPPPPLPPMTGGQPPLPPAM- 293
                     ||||.|    |......||...|||.|....:|   ||||.||   |:.|.||.|
 Worm   256 YQGQYPPVPPPPPSVTPMPPPMPPTPGMTPRPPPPPSSGMWP---PPPPPPP---GRTPGPPGMP 314

  Fly   294 GIPPPPRMMQPNAWAPPGMPAPPPRPPP----TNWRPPPVP----------FPPTPYARPYQP 342
            |:||||   .|:.:.||||...||.|||    ....|||.|          :||.|.:||..|
 Worm   315 GMPPPP---PPSRFGPPGMGGMPPPPPPGMRYPGGMPPPPPPRYPSAGPGMYPPPPPSRPPAP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	57/72 (79%)
		RRM2_SF3B4	99..181	CDD:409772	67/81 (83%)
sap-49	NP_001379265.1	RRM1_SF3B4	15..88	CDD:409771	57/72 (79%)
		RRM2_SF3B4	99..181	CDD:409772	67/81 (83%)