DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spx and bru3

DIOPT Version :9

Sequence 1:	NP_511058.1	Gene:	Spx / 31558	FlyBaseID:	FBgn0015818	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_001369050.1	Gene:	bru3 / 39527	FlyBaseID:	FBgn0264001	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	82/338 - (24%)
Similarity:	128/338 - (37%)	Gaps:	89/338 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 IMNMIKLYGKP-------IRVNKA--------SAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSA 122
            ::::|:|.|:|       :.:|:|        .:..::||  ..:|:|.|..:..|..:...|..
  Fly     1 MVHIIELVGQPKVEFAQQVTMNRALQLKPAENESRSEHLD--RKLFVGMLSKQQTEDDVRQIFHP 63

  Fly   123 FGVILQTPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYL---CNRPISVSYAFKKDHKG 184
            ||.| :...|:|.|: |.||..||:.|.|.:.:.:|:..::|...   .:..:.|.||   |.:.
  Fly    64 FGTI-EECTILRGPD-GASKGCAFVKFGSQQEAQSAITNLHGSQTMPGASSSLVVKYA---DTEK 123

  Fly   185 ER-------------------------HGSAAERLLAAQNPSTHADRPHQLFADAPVQTMMPQMP 224
            ||                         :|:.|::...|...:..|..|.   :.|.....|..:.
  Fly   124 ERQIRRMQQMAGHMNLLNPFVFNQFSPYGAYAQQQQQAALMAAAATAPG---SAAAYMNPMAALA 185

  Fly   225 GQIPAQMPGQMMPPPMMAPPPPVVPVSNNNMGMLAP---------------------PPPVPQPA 268
            .|||..:.|...||.:   |.|.:|  |.|||...|                     ...:||.|
  Fly   186 TQIPHGLNGTGQPPSL---PSPTMP--NFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQTA 245

  Fly   269 ----PFPATIPPPPLPPMTGGQPPLPPAM-GIPPPPRMMQPNAWA--PPGMPAPPPRPPPTNWRP 326
                |...||||..||  .|....|..|. |:||.|.:..|..:.  |..:|.|.....||. |.
  Fly   246 FPGHPLHLTIPPQGLP--NGDAATLQHAFPGLPPFPGVAFPAVYGQFPQALPPPLAAVAPTQ-RE 307

  Fly   327 PPVPFPPTPYARP 339
            ..:.||....:.|
  Fly   308 DFLMFPGCSISGP 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:240780	4/21 (19%)
Spx	NP_511058.1	RRM2_SF3B4	99..181	CDD:240781	23/84 (27%)
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043	24/86 (28%)
		ELAV_HUD_SF	43..404	CDD:273741	74/294 (25%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	1/2 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010