Protein Alignment Spx and pabpc1b

DIOPT Version :10

• Sequence 1: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_957176.1
• Gene: pabpc1b / 393856
• ZFINID: ZDB-GENE-050308-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 544
• Identity: 118/544 - (21%)
• Similarity: 175/544 - (32%)
• Gaps: 210/544 - (38%)

  Fly     5 PIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADY 69
            |.|.....|::|.|.|...|:|.:|:|.|..||.::::.:.:|.:|:...||.:|.|....||:.
Zfish     3 PSAPSYPMASLYVGDLHQDVTEAMLYEKFSPAGAILSIRVCRDMITRRSLGYAYVNFQQPADAER 67

  Fly    70 GIKIMNMIKLYGKPIRV--NKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVIL----- 127
            .:..||...:.|:|:|:  ::.....:...|| ||||.|||..:|.|.|||||||||.||
Zfish    68 ALDTMNFDVIKGRPVRIMWSQRDPSLRKSGVG-NIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

  Fly   128 ----------------------------------------------------------------- 127
                                                                             
Zfish   132 CDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIK 196

  Fly   128 ---------------------QTPKIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRP 171
                                 .:.::|.| |.|||:.|.|::|...|.:..|:|.|||:.:..:.
Zfish   197 NFGEDMDDDKLKDIFSKYGNAMSIRVMTD-ENGKSRGFGFVSFERHEDAQRAVDEMNGKEMNGKL 260

  Fly   172 ISVSYAFKK------------DHKGER---------------HGSAAERLLAAQNP--------- 200
            |.|..|.||            ..|.:|               .|...|||....:|
Zfish   261 IYVGRAQKKVERQTELKRKFEQMKQDRMTRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKV 325

  Fly   201 --------------------STHA--DRPHQLFADAPVQTMMPQMPGQIPAQMPGQMM------- 236
                                :|.|  :...::.|..|:...:.|...:..|.:..|.|
Zfish   326 MMDGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVR 390

  Fly   237 --PPPMM---APPPP------VVPVSNN--------NMGMLAPP--------------------- 261
              |.|::   .|.||      .:|.:.|        .:..|.|.
Zfish   391 AVPNPVINPYQPAPPSGYFMAAIPQAQNRAAYYPTSQLAQLRPSPRWTTQGVRPQHFQNMPGTMR 455

  Fly   262 PPVPQPAPFPATIPPPPLPPMTGGQPPLPPAMGIPPPPRMMQPNAWAPP--GMP----APPPRPP 320
            |..|:|..|....|...:|.|...|......||  |.|......|.|||  |:|    ||..|.|
Zfish   456 PSAPRPQTFSTMRPASQVPRMMSTQRVATQTMG--PRPSTAAAAASAPPVRGVPQYKYAPSVRNP 518

  Fly   321 P--TNWRPPPVPFPPTPYARPYQP 342
            .  .|.:|......|..:.:..:|
Zfish   519 QQHMNTQPQVTMQQPAVHVQGQEP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	23/74 (31%)
		RRM2_SF3B4	99..181	CDD:409772	41/184 (22%)
pabpc1b	NP_957176.1	PABP-1234	11..613	CDD:130689	116/536 (22%)