Protein Alignment Spx and PABPC1L2A

DIOPT Version :10

• Sequence 1: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001012995.1
• Gene: PABPC1L2A / 340529
• HGNCID: 27989
• Length: 200
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 68/197 - (34%)
• Similarity: 110/197 - (55%)
• Gaps: 17/197 - (8%)

  Fly    13 ATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMI 77
            |::|.|.|..:|:|.:|:|.|..|||::::.:.:|::|:...||.:|.:....||...::.:|..
Human     2 ASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFD 66

  Fly    78 KLYGKPIRV--NKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGK 140
            .:.|:|:|:  ::.....:...|| |:||.||...:|.|.||:.|||||.||.. |:..| |.|
Human    67 VIKGRPVRIMWSQRDPSLRKSGVG-NVFIKNLGKTIDNKALYNIFSAFGNILSC-KVACD-EKG- 127

  Fly   141 SKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFK--KDHKGERHGSAAERLLAAQNPSTH 203
            .|.:.|::|...|:::.|:|.|||.:|..|.|.|. .||  |:.:.||...|.:        ||.
Human   128 PKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVG-RFKSHKEREAERGAWARQ--------STS 183

  Fly   204 AD 205
            ||
Human   184 AD 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	22/74 (30%)
		RRM2_SF3B4	99..181	CDD:409772	36/83 (43%)
PABPC1L2A	NP_001012995.1	PABP-1234	2..>196	CDD:130689	68/197 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..200		7/24 (29%)