Protein Alignment Spx and Sf3b4

DIOPT Version :10

• Sequence 1: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_694693.1
• Gene: Sf3b4 / 107701
• MGIID: 109580
• Length: 424
• Species: Mus musculus
• Alignment Length: 418
• Identity: 250/418 - (59%)
• Similarity: 275/418 - (65%)
• Gaps: 81/418 - (19%)

  Fly     1 MAAGPIAERNQDATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEE 65
            ||||||:|||||||:|.||||:||||.||||||:|||||||.||||||||..|||||||||||||
Mouse     1 MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65

  Fly    66 DADYGIKIMNMIKLYGKPIRVNKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQTP 130
            ||||.||||||||||||||||||||||.|||||||||||||||.|:|||||||||||||||||||
Mouse    66 DADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTP 130

  Fly   131 KIMRDPETGKSKSFAFINFASFEASDAAMDAMNGQYLCNRPISVSYAFKKDHKGERHGSAAERLL 195
            ||||||:||.||.:||||||||:|||||::||||||||||||:||||||||.|||||||||||||
Mouse   131 KIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLL 195

  Fly   196 AAQNPSTHADRPHQLFADAPVQTMMPQMPGQIPAQMPGQMMPPPMMAP----PPPVVPVSNNNMG 256
            |||||.:.||||||||||||..   |..|..:.:.: |..:|||.|.|    ||||.|......|
Mouse   196 AAQNPLSQADRPHQLFADAPPP---PSAPNPVVSSL-GSGLPPPGMPPPGSFPPPVPPPGALPPG 256

  Fly   257 M--LAPPPPVP------------------------QPAPF-PATIPPPPL--------------- 279
            :  ..||||:|                        .|.|| |..:|.|.:
Mouse   257 IPPAMPPPPMPPGAGGHGPPAAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGH 321

  Fly   280 ----PPMTGGQPPL----------PPAMGIPP--PP---RMMQPNAWAPPGMPAP---------- 315
                ||.:|||||.          ||.||:||  ||   .|..|....|.||..|
Mouse   322 PHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYT 386

  Fly   316 -PPRPPPTNWRPPPVPFPPTPYARPYQP 342
             ||||||..::..|:| ||.|..||..|
Mouse   387 GPPRPPPYGYQRGPLP-PPRPTPRPPVP 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	63/72 (88%)
		RRM2_SF3B4	99..181	CDD:409772	71/81 (88%)
Sf3b4	NP_694693.1	RRM1_SF3B4	15..88	CDD:409771	63/72 (88%)
		RRM2_SF3B4	99..181	CDD:409772	71/81 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..424		69/212 (33%)