Protein Alignment dtn and si:dkey-1d7.3

DIOPT Version :10

• Sequence 1: NP_001284933.1
• Gene: dtn / 31555
• FlyBaseID: FBgn0262730
• Length: 1407
• Species: Drosophila melanogaster
• Sequence 2: XP_073791296.1
• Gene: si:dkey-1d7.3 / 793262
• ZFINID: ZDB-GENE-091118-46
• Length: 1160
• Species: Danio rerio
• Alignment Length: 1241
• Identity: 301/1241 - (24%)
• Similarity: 465/1241 - (37%)
• Gaps: 298/1241 - (24%)

  Fly     6 LIIALQLSLAYSVEVHFEAPDSGFFLKHARQPPVTPEIANV------QTSSAVPPLRQRSSYDSV 64
            :||.|.||.|..::|...:.|.......|..|.|..:|.|.      :||..|..       :|.
Zfish     4 MIIMLCLSSAEGMKVVELSDDPRSMSPFAVLPSVNYQIINADYLLLRETSQDVMD-------NSS 61

  Fly    65 LSLDRFTVVET---TQPVSIRASYGPFSTKQTVPARYIVPDTMDSQSGDYMNNATLLELQQPNMH 126
            |...|...:.|   .|| :|..|:|..|.:|::|...|       .:|             |.:.
Zfish    62 LRAQRQPFILTGLNGQP-AINVSFGSMSLEQSIPLHMI-------HTG-------------PRIR 105

  Fly   127 LDISAHLVRSSVSQDAPVLRVLFHA----------------GADPGGHLQRQKVCVLLHVAMGSE 175
            ..|.|..||||    .|.|.|||:|                |.:.||::     ||.|: |....
Zfish   106 AFILARQVRSS----TPALYVLFYATGNRDDTSEGPIQNVPGQNEGGYM-----CVTLY-AFWES 160

  Fly   176 QPLKGRCMPEGEDGVCVAEVVVPLGWW-PQLPAPTQDGSGQAPPKVPQRYAQVSYSVFEPPLRNP 239
            :.::..|....:.|.|:..:.....|: |.....:.:..|.....|.:.|.|:..|        |
Zfish   161 KEIRDSCSISADGGFCLVHLRPEPSWFNPAGGRSSWEQRGDQRGNVAELYYQIRPS--------P 217

  Fly   240 E-QCEP---KVQIQP-------------LTTFAQVPLLAARTP-----YRMLRADDAVTFLLPQH 282
            . ||.|   |::..|             :.....|.||  |:|     :..||...||.......
Zfish   218 SGQCVPQESKIRRGPQHGELGRQVYGTSMKKIGTVNLL--RSPPGNPTFMRLRLGGAVIIQTSSK 280

  Fly   283 PLYPLSRLHVPVFLHQYPDQRVAAFTVRARVKAGLKILGATAS-TDQWSVSVEK-ENPKHTTARV 345
            ||.........|||..  ...|..|.:||..|.|:....|..| ..||.:::|. ......|..|
Zfish   281 PLKTTDTATFYVFLSS--TSPVEHFILRATSKKGMSFSTARPSDAHQWDITLEPGRGSDAQTISV 343

  Fly   346 TAFRKEAESSLESGGNLTSEVFEVFSWLLEV------AEDTNDIVDGGKIVWSVTHVYDTPKDKD 404
            |..:|...:|...              ||||      .|:.:|.::...|.|.:    :.|.:
Zfish   344 TCQKKSTFASKRG--------------LLEVLQLDFETEEQSDQLESQMITWRL----ELPGN-- 388

  Fly   405 SGELVIPDDNKKRLIAKLEINKDDIQAVLPMAKI---WEVMNTAVLTGRQVAQAMKVFIVSQAGK 466
                :|.|:...|:..   |.:|.: .:.|:..:   .|::|||:|||::|:..:||..|...|.
Zfish   389 ----MIRDEGTMRIYT---IQRDYV-GIAPLITVGNDTELLNTAMLTGKKVSVPVKVLGVEADGS 445

  Fly   467 VADVTLQSSCHAEDESVIKVSSSCSSVYVDGSEQRGSSNASVIVKYGTYVGVAKFIVWMPEFPLE 531
            :.|:|..|.|.:.|:.|:|||..|.||||:|.|.||.....|...|.......:..||.|..||:
Zfish   446 ITDITNSSRCRSSDQDVLKVSERCDSVYVNGKETRGRVKTMVNFTYSYLSAQLEVNVWTPRLPLQ 510

  Fly   532 VYISDFRLSQIKGWKVTDDNHYLHNKQSRRRKKRSYVWGQHGTNYYNNLGADKTICRARYQQSPV 596
            :.:||..|||||.|:|....          .||.|  |.....:.....|     |..:||.|.:
Zfish   511 MEMSDTELSQIKAWRVPVSG----------SKKVS--WDTEEDDERKGRG-----CMLQYQHSLI 558

  Fly   597 EVYAKFLAVDQNSGRTS--YFISRRTGLRVTDLVQPLLRVADPKIASLK-GRILQGKSMGRTDVQ 658
            .|...|.|...:..|.|  ||:.....:.||.||:..|||.|..||.|: |.:|.||::|.|.||
Zfish   559 RVLTVFTAESPDPSRPSPAYFLGSDWQVDVTRLVRYFLRVGDTSIARLQAGTVLTGKAVGVTTVQ 623

  Fly   659 VLSPITGRVIGTKEIRVGSDKVNLSKLIVRVISGLQLTISPDNTIENGYLAETSVTHKLTAQYQE 723
            |:||::..::..:.|||..|||::::|.|:::|||.|.:..........:|:|:....:....||
Zfish   624 VMSPLSSSILAERVIRVLDDKVSITELGVQLVSGLSLNLQLSTGSNRAIVAKTTTQEIIHYPKQE 688

  Fly   724 GLLDIDLEFTDGSKTPLRDIAVEDYFLLVESLDTEVVAFAPMLASHHPRVIAVGEGNGNLLRVTL 788
            .::...|:|:|||:|||.......|.|.:.|:|.:||:...:..|.. .|:|.|||.|.|||..|
Zfish   689 AVVGCWLKFSDGSQTPLDLYDPIGYSLSISSMDPKVVSVQTIQGSVF-AVVAEGEGQGLLLRAEL 752

  Fly   789 LLSEECRQRR------------------------------------------------------- 798
            .:.|.|::.:
Zfish   753 AICEACQKSKRKSKLAVGGGMVKVKFPSDEQLSGTGKKESIRVTDDVDKDSDSKLTLTSPLNILQ 817

  Fly   799 ----------GTLSSSKQNKSNAAPLASALASIE-VDFNNVDIVSKQEAIQNDGTVGRERKNYRQ 852
                      |..|::|.|...|  :...:::|: ::|.|..:::|..|.:...|||.:.:....
Zfish   818 HTIMQESTTSGIKSATKSNLQEA--IGGGVSTIKAINFLNKTLITKPIADRALVTVGPKSQIKNA 880

  Fly   853 TGDLADIIVGIPLRDSSQLYEPTVQARQHRGSIQAVHKGHHGKGLAGTGTMTTMELGMYVLLTAF 917
            .|:|.: ....|........||.:   .....||..            ...|.:|:.:|.|:...
Zfish   881 YGNLLE-KPNFPFPPEEPKREPPL---VESNLIQMF------------SVFTDIEVCIYALVGLS 929

  Fly   918 CFAIIVFVISCVVYASKFRPAMIESGLDPLSAGKSNGSGGSGGFRDVRLKESTTNAHDWVWLGRS 982
            |.|:|..::.|...:::.|...                      ..::.:....:.|.||.|  |
Zfish   930 CLAMIAVLLHCATSSARTRNRK----------------------TPIQCQGQHEHRHHWVRL--S 970

  Fly   983 TIDRQSIVAETNTHLNPRDSRMRITSNPIVNYDNGRRVSSFDQQPKLQTHIVPASNLNKQHADHY 1047
            |...||......|..||  ........|       |.:.:......:|...:||
Zfish   971 TAAEQSRAVPIATASNP--GTQAAVEMP-------RAIQTSVNPEMIQPREIPA----------- 1015

  Fly  1048 LANERKDNALDYKP-PVPPHRNVGARACLPVQPVLGTGSVKDAAPNKRHSQLYRREHLQNSDSNA 1111
            :|.|.:...|..:. .:||.|...|    |:.|:....:...|.|       .|.|.|.:..|..
Zfish  1016 IAGEERTATLGRRTNTLPPRREPMA----PLPPMAVRSATLLAKP-------VRSEPLHSPTSKR 1069

  Fly  1112 NSQQST 1117
            |..|.|
Zfish  1070 NQVQFT 1075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dtn	NP_001284933.1	TMEM132D_N	18..170	CDD:464813	43/176 (24%)
		TMEM132	440..796	CDD:465003	127/358 (35%)
		TMEM132D_C	881..982	CDD:464814	15/100 (15%)
si:dkey-1d7.3	XP_073791296.1	None