DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sqh and mlc-4

DIOPT Version :9

Sequence 1:	NP_001284928.1	Gene:	sqh / 31554	FlyBaseID:	FBgn0003514	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_497700.1	Gene:	mlc-4 / 175440	WormBaseID:	WBGene00003372	Length:	172	Species:	Caenorhabditis elegans

Alignment Length:	175	Identity:	126/175 - (72%)
Similarity:	149/175 - (85%)	Gaps:	6/175 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSRKTAGRRATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGK 65
            |:||||..||    :|.||||||||||||||||.||||||||||||||||:::|||.||.|||||
Worm     1 MASRKTVNRR----QRPQRATSNVFAMFDQAQIQEFKEAFNMIDQNRDGFIDQEDLKDMFASLGK 61

  Fly    66 NPTDDYLDGMMNEAPG--PINFTMFLTLFGERLQGTDPEDVIKNAFGCFDEENMGVLPEDRLREL 128
            ..|:.::|.|:|||||  |||||||||||||:|.|||||:||:|||.||||:|.|.|.|:.||||
Worm    62 EVTEQFIDSMINEAPGAQPINFTMFLTLFGEKLTGTDPEEVIRNAFQCFDEDNSGKLNEEHLREL 126

  Fly   129 LTTMGDRFTDEDVDEMYREAPIKNGLFDYLEFTRILKHGAKDKDE 173
            |||||:|:::|.|||::|:||||.|.|||:||||:||||.|||||
Worm   127 LTTMGERYSEEQVDELFRDAPIKGGQFDYVEFTRMLKHGTKDKDE 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqh	NP_001284928.1	FRQ1	15..170	CDD:227455	114/156 (73%)
mlc-4	NP_497700.1	FRQ1	17..168	CDD:227455	110/150 (73%)
		EFh	31..>75	CDD:238008	30/43 (70%)
		EFh	103..163	CDD:238008	39/59 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164537
Domainoid	1	1.000	57	1.000	Domainoid score	I7310
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68515
Inparanoid	1	1.050	258	1.000	Inparanoid score	I1937
Isobase	1	0.950	-	0	Normalized mean entropy	S526
OMA	1	1.010	-	-		QHG51980
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	1	1.000	-	-		oto17600
orthoMCL	1	0.900	-	-		OOG6_103056
Panther	1	1.100	-	-	LDO	PTHR23049
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4770
SonicParanoid	1	1.000	-	-		X162
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790