DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sqh and MYL9

DIOPT Version :9

Sequence 1:	NP_001284928.1	Gene:	sqh / 31554	FlyBaseID:	FBgn0003514	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_006088.2	Gene:	MYL9 / 10398	HGNCID:	15754	Length:	172	Species:	Homo sapiens

Alignment Length:	174	Identity:	140/174 - (80%)
Similarity:	157/174 - (90%)	Gaps:	3/174 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSRKTAGRRATTKKRAQRATSNVFAMFDQAQIAEFKEAFNMIDQNRDGFVEKEDLHDMLASLGK 65
            |||::...:  |||||.|||||||||||||:||.||||||||||||||||::|||||||||||||
Human     1 MSSKRAKAK--TTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGK 63

  Fly    66 NPTDDYLDGMMNEAPGPINFTMFLTLFGERLQGTDPEDVIKNAFGCFDEENMGVLPEDRLRELLT 130
            ||||:||:|||:|||||||||||||:|||:|.||||||||:|||.|||||..|.:.||.||||||
Human    64 NPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLT 128

  Fly   131 TMGDRFTDEDVDEMYREAPI-KNGLFDYLEFTRILKHGAKDKDE 173
            |||||||||:|||||||||| |.|.|:|:||||||||||||||:
Human   129 TMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sqh	NP_001284928.1	FRQ1	15..170	CDD:227455	130/155 (84%)
MYL9	NP_006088.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		11/20 (55%)
MYL9	NP_006088.2	FRQ1	19..169	CDD:227455	125/149 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156477
Domainoid	1	1.000	63	1.000	Domainoid score	I10246
eggNOG	1	0.900	-	-		E2759_KOG0031
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2839
Isobase	1	0.950	-	0	Normalized mean entropy	S526
OMA	1	1.010	-	-		QHG51980
OrthoDB	1	1.010	-	-		D1435392at2759
OrthoFinder	1	1.000	-	-		FOG0000218
OrthoInspector	1	1.000	-	-		otm40303
orthoMCL	1	0.900	-	-		OOG6_103056
Panther	1	1.100	-	-	O	PTHR23049
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4770
SonicParanoid	1	1.000	-	-		X162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.750