Protein Alignment Efr and Slc35b4

DIOPT Version :10

• Sequence 1: NP_572299.1
• Gene: Efr / 31553
• FlyBaseID: FBgn0029849
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_067410.1
• Gene: Slc35b4 / 58246
• MGIID: 1931249
• Length: 331
• Species: Mus musculus
• Alignment Length: 317
• Identity: 173/317 - (54%)
• Similarity: 227/317 - (71%)
• Gaps: 19/317 - (5%)

  Fly    14 VFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVRPKIALKDYVILVALFF 78
            ||.||||||:||||:.:..||.||::|||||||||:||.:|.:......|.|.::.|.|:|.:||
Mouse    10 VFAGCCSNVIFLELLARTHPGCGNIVTFAQFLFIAVEGFLFEANLGRKPPAIPIRYYAIMVTMFF 74

  Fly    79 GANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAGIILCTLVSS 143
            ..:|.||||.|.||.||||||||||||:||||:||::|||||::.:|:|:|:::|||.:||.:|:
Mouse    75 TVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSMFKYTSIALVSAGIFICTFMSA 139

  Fly   144 GDVKDNTHHSLKVDTSYSD------FFWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEAL 202
            ..|        .|.|..||      |.||.:||..||.|||::|.|||:||.:|:::|||..|||
Mouse   140 KQV--------TVQTGLSDKDGFQAFAWWLLGIAALTFALLMSARMGIFQETLYRQFGKHSKEAL 196

  Fly   203 FFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQYVCISA 267
            |:.|.||||||:.:|.:|..|..:...||...||::|.     ..|:|.||||.|||||||||..
Mouse   197 FYNHALPLPGFIFLASDIYDHVVLFNKSELYQVPVIGV-----TMPVMWFYLLMNVVTQYVCIRG 256

  Fly   268 VYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANV 324
            |::|||||.||||||||||||||||:|||:||:|.||:.||:||..||.||:::..|
Mouse   257 VFILTTECTSLTVTLVVTLRKFVSLIFSILYFQNQFTMWHWLGTSFVFIGTLMYTEV 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efr	NP_572299.1	UAA	6..325	CDD:462479	173/317 (55%)
Slc35b4	NP_067410.1	UAA	2..314	CDD:462479	173/317 (55%)
		Mediates endoplasmic reticulum retention. /evidence=ECO:0000250|UniProtKB:Q969S0	326..331