DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Efr and slc35b4

DIOPT Version :9

Sequence 1:	NP_572299.1	Gene:	Efr / 31553	FlyBaseID:	FBgn0029849	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_997817.2	Gene:	slc35b4 / 323737	ZFINID:	ZDB-GENE-030131-2457	Length:	331	Species:	Danio rerio

Alignment Length:	338	Identity:	183/338 - (54%)
Similarity:	246/338 - (72%)	Gaps:	13/338 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LKALLGMLFVFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVRPKIALKD 69
            :..|..:..||:|||||||||||:::..||.||::|||||.||||||.:|.:.|...:|:|.|.:
Zfish     1 MNTLFAVTLVFVGCCSNVVFLELLVRDFPGCGNIVTFAQFAFIALEGFIFETNFGRKKPQIPLSN 65

  Fly    70 YVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITAG 134
            |||:|.:||..:|.||||.||||.||||||||||||:||||:||::|||||::.:|.|:.:::.|
Zfish    66 YVIMVTMFFTVSVINNYALNFNIAMPLHMIFRSGSLIANMILGIIILKKRYSMSKYLSIVLVSVG 130

  Fly   135 IILCTLVSSGDV---KDNTHHSLKVDTSYSDFFWWTVGIGLLTIALLVTAYMGIYQEVIYKKYGK 196
            |.:||::|:..|   |..|..    |..|: |..|.:||.:||.|||::|.|||:||.:||||||
Zfish   131 IFICTIMSAKQVNVEKGGTEE----DGVYA-FMHWLLGIAMLTFALLMSARMGIFQETLYKKYGK 190

  Fly   197 HPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCNVVTQ 261
            |..||||:.|.|||||||:::.||..|..:...|.|:.||::|.     ..|:|.||||.||:||
Zfish   191 HSKEALFYNHCLPLPGFLLLSTNIYNHAVLFSQSSPMEVPVIGL-----SMPVMWFYLLMNVITQ 250

  Fly   262 YVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFANVIN 326
            ||||..|::|||||||||||||||||||:||:.||:||:||||..|||||.:||.||:|:..|::
Zfish   251 YVCIRGVFILTTECASLTVTLVVTLRKFLSLIISILYFQNPFTAWHWVGTAVVFLGTLLYTEVLS 315

  Fly   327 QVRDAYRARSSRK 339
            .:..|::...:.|
Zfish   316 SIPAAFKGYKADK 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Efr	NP_572299.1	UAA	6..325	CDD:285625	180/321 (56%)
Efr	NP_572299.1	EamA	91..321	CDD:304911	132/232 (57%)
slc35b4	NP_997817.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586330
Domainoid	1	1.000	365	1.000	Domainoid score	I879
eggNOG	1	0.900	-	-		E1_KOG1583
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5799
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2082
OMA	1	1.010	-	-		QHG54056
OrthoDB	1	1.010	-	-		D1209974at2759
OrthoFinder	1	1.000	-	-		FOG0004206
OrthoInspector	1	1.000	-	-		oto39601
orthoMCL	1	0.900	-	-		OOG6_104444
Panther	1	1.100	-	-	LDO	PTHR10778
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1792
SonicParanoid	1	1.000	-	-		X2952
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800