DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Efr and AgaP_AGAP011493

DIOPT Version :9

Sequence 1:	NP_572299.1	Gene:	Efr / 31553	FlyBaseID:	FBgn0029849	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_317807.4	Gene:	AgaP_AGAP011493 / 1278374	VectorBaseID:	AGAP011493	Length:	337	Species:	Anopheles gambiae

Alignment Length:	342	Identity:	217/342 - (63%)
Similarity:	268/342 - (78%)	Gaps:	16/342 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NLKALLGMLFVFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVRPKIALK 68
            |:||.|.:..||:|||||||||||:::||||:||||||.|||||||||.:||||..||||:|.||
Mosquito     3 NMKAALAIALVFVGCCSNVVFLELLVKIDPGSGNLITFLQFLFIALEGFLFTSKCGTVRPRIGLK 67

  Fly    69 DYVILVALFFGANVCNNYAFNFNIPMPLHMIFRSGSLMANMIMGIVLLKKRYNLRQYSSVAMITA 133
            ||.|||.:||.|:|||||||:||||||||||||:|||:|||:|||::|||||:..:|.||.|||.
Mosquito    68 DYTILVVMFFVASVCNNYAFDFNIPMPLHMIFRAGSLIANMVMGILILKKRYDFSKYLSVGMITL 132

  Fly   134 GIILCTLVSSGDVKDNTHHSLKVDTSYSD------FFWWTVGIGLLTIALLVTAYMGIYQEVIYK 192
            ||::||:||...|:     |.:|..:.:|      |||||:||.|||:||.|:|.||:||||:||
Mosquito   133 GIVICTIVSGTKVE-----STQVLKNAADEDPMSVFFWWTLGIALLTLALFVSARMGLYQEVLYK 192

  Fly   193 KYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAVPLLGAIGLEWKFPLMLFYLLCN 257
            :|||||.||||:||:||||.|.::||||.:|..:|.:|...|:|.||.     ..|:...|||.|
Mosquito   193 RYGKHPKEALFYTHLLPLPFFALLAGNIWEHVQLANASPLQAIPALGV-----SLPITWLYLLGN 252

  Fly   258 VVTQYVCISAVYVLTTECASLTVTLVVTLRKFVSLLFSIIYFRNPFTLNHWVGTILVFFGTILFA 322
            |:|||||||:||||||||:||||||||||||||||||||:||.||||:.||:||||||.|||:|.
Mosquito   253 VLTQYVCISSVYVLTTECSSLTVTLVVTLRKFVSLLFSIVYFSNPFTVQHWIGTILVFVGTIIFT 317

  Fly   323 NVINQVRDAYRARSSRK 339
            .|:.:||.|......:|
Mosquito   318 EVVGKVRSALAPAEEKK 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Efr	NP_572299.1	UAA	6..325	CDD:285625	211/324 (65%)
Efr	NP_572299.1	EamA	91..321	CDD:304911	148/235 (63%)
AgaP_AGAP011493	XP_317807.4	UAA	5..319	CDD:285625	211/323 (65%)
AgaP_AGAP011493	XP_317807.4	EamA	90..316	CDD:304911	148/235 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	424	1.000	Domainoid score	I1873
eggNOG	1	0.900	-	-		E1_KOG1583
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5799
Inparanoid	1	1.050	439	1.000	Inparanoid score	I3574
OMA	1	1.010	-	-		QHG54056
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004206
OrthoInspector	1	1.000	-	-		oto109908
Panther	1	1.100	-	-	LDO	PTHR10778
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2952
TreeFam	1	0.960	-	-
	12	11.930