Protein Alignment Btnd and VNN1

DIOPT Version :9

• Sequence 1: NP_572298.1
• Gene: Btnd / 31552
• FlyBaseID: FBgn0029848
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_004657.2
• Gene: VNN1 / 8876
• HGNCID: 12705
• Length: 513
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 140/466 - (30%)
• Similarity: 209/466 - (44%)
• Gaps: 84/466 - (18%)

  Fly    28 TYTAAVVEHSQPVGDSPRARTTSAS------------ESFQKIIREVGD--VDIIVFPEHIL--- 75
            |:||||.||:..:   |.|..|..|            :..:..|....|  ..|||.||..:
Human    24 TFTAAVYEHAAIL---PNATLTPVSREEALALMNRNLDILEGAITSAADQGAHIIVTPEDAIYGW 85

  Fly    76 --NSQATATF---VPHESQNITPCY------QTDYELFLIELSCSARANHLYVVINVVEKELCAH 129
              |..:...:   :|....|..||.      ||..:   ..|||.|:.|.:|||.|:.:|:.|
Human    86 NFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPVQ---ERLSCLAKNNSIYVVANIGDKKPC-- 145

  Fly   130 GAGSDTYNP-CPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWRHEYVSTSVLRSPDISIFRTDFGV 193
                ||.:| ||..|...:||:||||.:|::|:||.|.:|:..|. ..:|.:.|:|..|.|.||
Human   146 ----DTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGEN-QFNVPKEPEIVTFNTTFG- 204

  Fly   194 TFGHFICFDMLFYDPAMKLVKEHKITDIVYPTYWFSELPFLGAVQLQEGWAFGNDVNVLAADASN 258
            :||.|.|||:||:|||:.|||:..:..||:||.|.:.||.|.||:....||.|..||.||::...
Human   205 SFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMNVLPHLSAVEFHSAWAMGMRVNFLASNIHY 269

  Fly   259 PDGRTSGSGIYAGRGGRLVAEIFEQPTTKLLIAEVPKREHGQLAPTFTPIFEPQRKTQRLTGLAT 323
            |..:.:||||||....|......:....|||::::...      |:.:.:.   ..|...:.:..
Human   270 PSKKMTGSGIYAPNSSRAFHYDMKTEEGKLLLSQLDSH------PSHSAVV---NWTSYASSIEA 325

  Fly   324 YRDNNVDIFESELLDDDF-------LSFERQLCHGSFCCTFSIERKVTSAAENELPSSGAKSYRY 381
            ....|.: |:..:..|:|       ::....:|....||..|.  |::....||:         |
Human   326 LSSGNKE-FKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSY--KMSENIPNEV---------Y 378

  Fly   382 RIGVYWGNETTVIGVDRTEQATCALFACTDVRLASCGYIYPENEEVINTHHFTKLSISGNFPAAP 446
            .:|.:.|.. ||.|  |.....|.|..|....|.:||    ::.|..:| .|...|:||.|
Human   379 ALGAFDGLH-TVEG--RYYLQICTLLKCKTTNLNTCG----DSAETAST-RFEMFSLSGTF---- 431

  Fly   447 RGRRLIMPSSL 457
             |.:.:.|..|
Human   432 -GTQYVFPEVL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	104/307 (34%)
VNN1	NP_004657.2	biotinidase_like	25..330	CDD:143591	105/327 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157432
Domainoid	1	1.000	106	1.000	Domainoid score	I6567
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4209
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		mtm8613
orthoMCL	1	0.900	-	-		OOG6_103493
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X969
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.660