Protein Alignment Btnd and UPB1

DIOPT Version :10

• Sequence 1: NP_572298.1
• Gene: Btnd / 31552
• FlyBaseID: FBgn0029848
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_057411.1
• Gene: UPB1 / 51733
• HGNCID: 16297
• Length: 384
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 72/325 - (22%)
• Similarity: 115/325 - (35%)
• Gaps: 103/325 - (31%)

  Fly    16 SSSHQLSKPEDPTYTAAVVEHSQPV-GDSPRARTTSASESFQKIIREVG---DVDIIVFPEHILN 76
            ::..||.:|.  .....:|::..|: .::|.|...||.....|.|.||.   .|:||.|.|
Human    61 AAEEQLRRPR--IVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQE---- 119

  Fly    77 SQATATFVPHESQNITPCYQTDYELFLIELSCSAR------------ANHLYVVINVVEKELCAH 129
                |..:|.       .:.|..:|...|.:.||.            .||..||::.:.:....|
Human   120 ----AWTMPF-------AFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEH 173

  Fly   130 GAGSDTYNPCPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWR------HEYVSTSVLRSPDISIFR 188
            |   |.          .:||.||....|.::.:.||.|:.|      ..|.....|..|   :|:
Human   174 G---DV----------LWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHP---VFQ 222

  Fly   189 TDFG-----VTFGHFICFDMLFY---------DPAMKL----------------VKEHKITDIV- 222
            |.||     :.:|.....:.|.|         :|:..:                :..|..|..:
Human   223 TQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAIN 287

  Fly   223 ------YPTYWFSELPFLGAVQLQE-GWAFGNDVNVLAADASNPDGRTSGSGIYAGRGGRLVAEI 280
                  :|..:.|.   .|....|: |:.:|:.. |.|.|:|    ||  .|:...|.|.|||::
Human   288 RVGTEHFPNEFTSG---DGKKAHQDFGYFYGSSY-VAAPDSS----RT--PGLSRSRDGLLVAKL 342

  Fly   281  280
            Human   343  342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	69/312 (22%)
		Vanin_C	325..511	CDD:465946
UPB1	NP_057411.1	ML_beta-AS	9..371	CDD:143611	72/325 (22%)