Protein Alignment Btnd and Vnn1

DIOPT Version :10

• Sequence 1: NP_572298.1
• Gene: Btnd / 31552
• FlyBaseID: FBgn0029848
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001020794.1
• Gene: Vnn1 / 29142
• RGDID: 1310075
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 157/571 - (27%)
• Similarity: 231/571 - (40%)
• Gaps: 146/571 - (25%)

  Fly    28 TYTAAVVEHS--------QPVGDSP------------RARTTSASESFQKIIREVGDVDIIVFPE 72
            |:.|||.||:        .||..|.            .....||::.         ...|||.||
  Rat    26 TFLAAVYEHAVILPKVTLLPVSHSEALALMNQNLDLLEGAILSAAKQ---------GAHIIVTPE 81

  Fly    73 H-ILNSQATATF-------VPHESQNITPCYQTDYELF-----LIELSCSARANHLYVVINVVEK 124
            . |...|.|...       :|....|..||  .:.|.|     ...|||.|:.|.:|||.|:.:|
  Rat    82 DGIYGVQFTRDTIYPYLEDIPDPQVNWIPC--DNPERFGSTPVQERLSCLAKNNSIYVVANMGDK 144

  Fly   125 ELCAHGAGSDTYNPCPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWRHEYVSTSVLRSPDISIFRT 189
            :.|   ..||::  ||..|...:||:||||.||::|:||.|.:|:..| ...:....|::..|.|
  Rat   145 KPC---NTSDSH--CPPDGRFQYNTDVVFDSRGKLVARYHKQNLFMGE-EQFNAPPEPEVVTFDT 203

  Fly   190 DFGVTFGHFICFDMLFYDPAMKLVKEHKITDIVYPTYWFSELPFLGAVQLQEGWAFGNDVNVLAA 254
            .|| .||.|.|||:||:|||:.||.|.::..|::||.|...||.|.|::....||.|..||.|||
  Rat   204 PFG-KFGIFTCFDILFHDPAVTLVTEFQVDTILFPTAWMDVLPHLAAIEFHSAWAIGMGVNFLAA 267

  Fly   255 DASNPDGRTSGSGIYAGRGGRLVAEIFEQPTT--KLLIAEVPKREHGQLAPTFTPI--------- 308
            :...|..|.:||||||....|  |..:::.|.  |||:|::...      |:.:|:
  Rat   268 NLHIPLRRMTGSGIYAPDSPR--AFHYDRKTQEGKLLLAQLDSH------PSHSPVNWTSYASSV 324

  Fly   309 -FEPQRKTQRLTGLATYRDNNVDIFESELLDDDFLSFERQ-------LCHGSFCCTFSIERKVTS 365
             ..|..|.:               |.|.:..|:|...|.:       :|....||..|.:.....
  Rat   325 EAPPTEKEE---------------FRSFVFFDEFTFVELKGITGNYTVCQNDLCCHLSYQMSEKR 374

  Fly   366 AAENELPSSGAKSYRYRIGVYWGNETTVIGVDRTEQATCALFACTDVRLASCGYIYPENEEVINT 430
            |.|           .|.:|.:.|.. ||.|  :.....|.|..|....|.:||    .:.:..:|
  Rat   375 ADE-----------VYALGAFDGLH-TVEG--QYHLQICILLKCKTTNLRTCG----SSVDTAST 421

  Fly   431 HHFTKLSISGNFPAAPRGRRLIMPSSLNALFLPVSVSDYEWIESPEAANNLDKTILVDLKLAKAQ 495
             .|...|:||.|     |.|.:.|.        |.:|:.:.  :|.....|....||.||  ...
  Rat   422 -RFEMFSLSGTF-----GTRYVFPE--------VLLSEVKL--APGEFQVLSDGRLVSLK--PTS 468

  Fly   496 NDLLTFAIWANYYTDIPSTHNLDHMQPNGTQSNPSTSASSTVSAFWILCVL 546
            ..:||..::...|                 :.:.:::|||.:.|..::.:|
  Rat   469 GPVLTVGLFGRLY-----------------EKDWASNASSDLIAHSLIIML 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	105/313 (34%)
		Vanin_C	325..511	CDD:465946	43/192 (22%)
Vnn1	NP_001020794.1	biotinidase_like	27..324	CDD:143591	106/322 (33%)
		Vanin_C	338..484	CDD:465946	41/198 (21%)