DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Btnd and Btd

DIOPT Version :9

Sequence 1:	NP_572298.1	Gene:	Btnd / 31552	FlyBaseID:	FBgn0029848	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_079571.1	Gene:	Btd / 26363	MGIID:	1347001	Length:	529	Species:	Mus musculus

Alignment Length:	508	Identity:	153/508 - (30%)
Similarity:	219/508 - (43%)	Gaps:	84/508 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LSFLLLSVL---FSSSHQLSKPEDPTYTAAVVEHSQPVGDSPRARTTSASESFQKIIREVG---- 63
            |.||..|.|   .||:.|..: |...|.|||.||...:..:| ....|..|:.:.:.:.:.
Mouse    19 LFFLGCSALALGVSSASQEHR-EAEYYVAAVYEHPSVLSPNP-LELVSRQEALELMKQNLDVYEQ 81

  Fly    64 --------DVDIIVFPE---HILNSQATA-----TFVPHESQNI---TPCYQ----TDYELFLIE 105
                    .|.||||||   |..|...|:     .|:|  |..:   .||.:    .|.|: |..
Mouse    82 QVMAAAQKGVQIIVFPEDGIHGFNFTRTSIYPFLDFMP--SPKLVRWNPCLEPFRFNDTEV-LQR 143

  Fly   106 LSCSARANHLYVVINVVEKELCAHGAGSDTYNPCPSSGVRYFNTNVVFDRRGRIVSRYRKTHLWR 170
            |||.|....:::|.|:..|:.|   ..||.  .||..|...|||||||...|.:|.||||.:|:.
Mouse   144 LSCMAIKGGMFLVANLGTKQPC---LSSDP--GCPQDGRYQFNTNVVFSDNGTLVDRYRKHNLYF 203

  Fly   171 HEYVSTSVLRSPDISIFRTDFGVTFGHFICFDMLFYDPAMKLVKEHKITDIVYPTYWFSELPFLG 235
            .....|..  :.|:..|.|.|...||.|.|||:||:|||::|:::.::..|||||.|.::||.|.
Mouse   204 EAAFDTPA--NVDLITFDTPFAGKFGVFTCFDILFFDPAVRLLRDFEVKHIVYPTAWMNQLPLLA 266

  Fly   236 AVQLQEGWAFGNDVNVLAADASNPDGRTSGSGIYAGRGGRLVAEIFEQPTTKLLIAEVPKREHG- 299
            |:::|:.:|....||||||:..:|....:||||:.........:: :.|...|:||:|.....|
Mouse   267 AIEIQKAFATAFGVNVLAANIHHPTLGMTGSGIHTPLKSFWYHDM-DDPKGHLIIAQVATNPQGL 330

  Fly   300 --------QLAPTF---------TPIFEPQRKTQRLTGLATYRDNNVDIFESELLDDDF------ 341
                    ::.|:.         .|..|...:.......|.:..|....|.||::.|:|
Mouse   331 TGTGNTTSEMDPSHRKFLKILSGDPYCEKDAQEVHCDEAAKWNVNVPPTFHSEMMYDNFTLVPVW 395

  Fly   342 -LSFERQLCHGSFCCTFSIERKVTSAAENELPSSGAKSYRYRIGVYWGNETTVIGVDRTEQATCA 405
             .....|:|..|.||....||...|   .||         |.:||:.|.. ||.|....:  |||
Mouse   396 GTEGHLQVCSNSLCCHLLYERPTLS---KEL---------YALGVFDGLH-TVHGTYYIQ--TCA 445

  Fly   406 LFACTDVRLASCGYIYPENEEVINTHHFTKLSISGNFPA-APRGRRLIMPSSL 457
            |..|..:...:||....|.|.:.:.|.:...|....||. ...|..|..|..|
Mouse   446 LVKCGGLGFDTCGQEITEAEGLFDFHLWGNFSTLYIFPLFLTSGMTLDTPDQL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Btnd	NP_572298.1	biotinidase_like	29..308	CDD:143591	101/323 (31%)
Btd	NP_079571.1	biotinidase_like	44..347	CDD:143591	101/314 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847842
Domainoid	1	1.000	96	1.000	Domainoid score	I7293
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4179
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276751at2759
OrthoFinder	1	1.000	-	-		FOG0001380
OrthoInspector	1	1.000	-	-		mtm8847
orthoMCL	1	0.900	-	-		OOG6_103493
Panther	1	1.100	-	-	O	PTHR10609
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5840
SonicParanoid	1	1.000	-	-		X969
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790