DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Igsf9b and dpr3

DIOPT Version :9

Sequence 1:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	59/288 - (20%)
Similarity:	86/288 - (29%)	Gaps:	118/288 - (40%)

- Green bases have known domain annotations that are detailed below.

  Rat   196 TSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQ-DALLTCRAEAY---- 255
            |...||..|     |...:.:...|:..|   |.|....|.|||..... :|::.||.::.
  Fly   212 TDAKRERSG-----AADEESQDADTSQSL---PIFDFGMPRNITGRTGHTEAIIKCRVDSLHDKS 268

  Rat   256 -------------PGNLTYTWYWQDENVYFQNDLKLRVRILIDG---TLIIFRVKPEDAGKYTCV 304
                         .|..|||           :|.:.:|....|.   ||.:.....:|:|.|.|.
  Fly   269 VSWIRKRDLHILTVGTATYT-----------SDKRFQVTESKDSREWTLHVKAPLAKDSGIYECQ 322

  Rat   305 PS-----------NSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPV------DAEP 352
            .:           |.:..||.|.|         |::.||.::...|....:.|.|      |..|
  Fly   323 VNTEPKMSMAFQLNIIEISPDAKA---------VISGPPDLHFKAGSAIILNCLVQQPSVKDIGP 378

  Rat   353 PATVVKWNK-----------DGRP-----------------------------------LQVEKN 371
                :.|.:           ||:|                                   :.:|..
  Fly   379 ----IYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDIMSEVDLQMEFATRIAMESQ 439

  Rat   372 LGWTLMEDGSIRIEEATEEALGTYTCVP 399
            ||.||  ...:||..|.....|.|||.|
  Fly   440 LGDTL--KSRLRISNAQTTDTGNYTCQP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273
		I-set	139..225	CDD:369462	6/28 (21%)
		Ig	229..321	CDD:386229	26/123 (21%)
		Ig	<353..414	CDD:386229	17/93 (18%)
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	20/97 (21%)
		IG_like	243..329	CDD:214653	20/96 (21%)
		Ig	350..464	CDD:299845	22/119 (18%)
		IG_like	<441..477	CDD:214653	11/27 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900