Protein Alignment vanin-like and Vnn1

DIOPT Version :10

• Sequence 1: NP_572297.1
• Gene: vanin-like / 31551
• FlyBaseID: FBgn0040069
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_035834.2
• Gene: Vnn1 / 22361
• MGIID: 108395
• Length: 512
• Species: Mus musculus
• Alignment Length: 591
• Identity: 164/591 - (27%)
• Similarity: 245/591 - (41%)
• Gaps: 136/591 - (23%)

  Fly     6 WWL--SVVLLILGLMPGMSQQAALAESDYYTAGVVEFKQSILSLSAWSDSLA---GYVEIINSEN 65
            |||  :.....|.::...|....||.  .|...|:..|.::|.:| .|::||   ..::::....
Mouse     5 WWLACAAAFSALCVLKASSLDTFLAA--VYEHAVILPKDTLLPVS-HSEALALMNQNLDLLEGAI 66

  Fly    66 ASA----TDIIVFPESTLNSAGST--TFVPN----PEDQIN--PCLSDP---NATYYEEFLVTLS 115
            .||    ..|||.||..:.....|  |..|.    |:.|:|  || .:|   .:|..:|   .||
Mouse    67 VSAAKQGAHIIVTPEDGIYGVRFTRDTIYPYLEEIPDPQVNWIPC-DNPKRFGSTPVQE---RLS 127

  Fly   116 CAARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLY-GEAK 179
            |.|:|.|.|:|.|:.:|:.|.  ..|:. |..:|...:||:||||.||.:|:||.|.::: ||.:
Mouse   128 CLAKNNSIYVVANMGDKKPCN--TSDSH-CPPDGRFQYNTDVVFDSQGKLVARYHKQNIFMGEDQ 189

  Fly   180 -NSTFLPELITFETDFGVTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTAVQTQ 243
             |....||.:||:|.|| .||.|.||||||:.||..|:.|..:...::|..|...||.|.|::..
Mouse   190 FNVPMEPEFVTFDTPFG-KFGVFTCFDILFHDPAVTLVTEFQVDTILFPTAWMDVLPHLAAIEFH 253

  Fly   244 QGWAYANDVNLLASGASRPSIGNSGSGIYHGRSGTLTSVMRQDSGERAIYVAQVP--------KY 300
            ..||....||.||:....||...:|||||...|..:....|: :.|..:..||:.        .:
Mouse   254 SAWAMGMGVNFLAANLHNPSRRMTGSGIYAPDSPRVFHYDRK-TQEGKLLFAQLKSHPIHSPVNW 317

  Fly   301 TRSRSLKKRAKRSLQEIQTRQVASSSSFYMKRDYVENYESELLKLDEGTSGAINRTICQGSFCCN 365
            |...|..:......||.|      |..|:.:..:||      ||   |..|  |.|:||...||:
Mouse   318 TSYASSVESTPTKTQEFQ------SIVFFDEFTFVE------LK---GIKG--NYTVCQNDLCCH 365

  Fly   366 FDIAWRSLGTATENGSYYSYRLGTYDGWRNENNVDAN-YIRNCALFTCSGDSIDDCGKLLPTEGE 429
            ...      ..:|..:...|..|.:||.   :.|:.. |::.|.|..|...::..||..:.|
Mouse   366 LSY------QMSEKRADEVYAFGAFDGL---HTVEGQYYLQICILLKCKTTNLRTCGSSVDT--- 418

  Fly   430 LQQSRVTFTRL-------AIGVTYPESREFLLFPDTLQDSLLPLEPSQFEWS------QRKPTED 481
                  .|||.       ..|..|       :||:.|. |.:.|.|.:|:.|      ..|||.
Mouse   419 ------AFTRFEMFSLSGTFGTRY-------VFPEVLL-SEVKLAPGEFQVSSDGRLVSLKPTS- 468

  Fly   482 SYVQEVRFALKETQELSNLLTFGIYGNYYDNECTFGVGTEEEQLACGYRSGSPGLRILGGWLAMP 546
                            ..:||.|::|..|..:......::                    ::|..
Mouse   469 ----------------GPVLTIGLFGRLYGKDWASNASSD--------------------FIAHS 497

  Fly   547 LIILAI 552
            |||:.|
Mouse   498 LIIMLI 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vanin-like	NP_572297.1	biotinidase_like	33..304	CDD:143591	100/298 (34%)
		Vanin_C	328..512	CDD:465946	47/197 (24%)
Vnn1	NP_035834.2	biotinidase_like	27..324	CDD:143591	103/308 (33%)
		Vanin_C	334..484	CDD:465946	49/209 (23%)