DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ca-alpha1T and Catsper3

DIOPT Version :9

Sequence 1:	NP_001259267.1	Gene:	Ca-alpha1T / 31550	FlyBaseID:	FBgn0264386	Length:	3218	Species:	Drosophila melanogaster
Sequence 2:	NP_001239416.1	Gene:	Catsper3 / 76856	MGIID:	1924106	Length:	395	Species:	Mus musculus

Alignment Length:	349	Identity:	89/349 - (25%)
Similarity:	163/349 - (46%)	Gaps:	64/349 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  2438 ENFHRCREEQEKEEKIRRAAKRALQ--MEKKRRRMHEPPYYTNYSPTRMFVHNVVTSKYFDLAIA 2500
            ::||. ...:.|...:...|..|||  :.|.:|:..|         .:.:...|:.|.:|.:.:.
Mouse     3 QHFHH-NPVRVKSGSLFATASEALQARLSKIKRKDKE---------CQAYFRKVIKSTFFQIVMI 57

  Fly  2501 AVIGLNVVTMAM--------EYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRW 2557
            ..:..|...:.:        |:::       ..::...||.:|::.|..|| |.:....|.||.:
Mouse    58 TTVTTNSFLLVLGTNYDIQFEFFR-------TFEVSELFFVSVYVCEFLMK-VYVDPITYWKDGY 114

  Fly  2558 NQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQ 2622
            |.|||.|:::..:..:|.:::.|       :...:.....::..|:|||:..:.|||.|:..|.:
Mouse   115 NILDVIILIILTIPYLLRKIKGN-------HSAYLHFADGIQSLRILKLISYSRGIRTLIIAVGE 172

  Fly  2623 ALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFANFGMAFLTLFRVATGDN 2687
            .:..|.::..|.|||.|:||.||..|||   .:|.      |:..::.|...||.|||.:||.|.
Mouse   173 TVYTVASVLTLLFLLMFVFAILGFCLFG---VTDR------GDLENWGNLASAFFTLFSLATVDG 228

  Fly  2688 WNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESHKQME 2752
            |..:.::..:          |...||..    |.::|:|:|.|:.:|:.|.|::.|.|:|.|:.|
Mouse   229 WTDLQEELDK----------RKFTVSRA----FTILFILLASFIFLNMFVGVMIMHTEDSMKKFE 279

  Fly  2753 DELDMEVEL----ERELV--REQE 2770
            .:|.:|..|    |::::  |:||
Mouse   280 RDLTLERNLAIMEEKQIILKRQQE 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921
		Ion_trans	2192..2448	CDD:278921	2/9 (22%)
		Ion_trans	2510..2728	CDD:278921	58/225 (26%)
Catsper3	NP_001239416.1	Ion_trans	49..269	CDD:366146	66/257 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810