DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ca-alpha1T and Catsper4

DIOPT Version :9

Sequence 1:	NP_001259267.1	Gene:	Ca-alpha1T / 31550	FlyBaseID:	FBgn0264386	Length:	3218	Species:	Drosophila melanogaster
Sequence 2:	XP_342942.5	Gene:	Catsper4 / 362623	RGDID:	1565213	Length:	448	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	82/329 - (24%)
Similarity:	144/329 - (43%)	Gaps:	62/329 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  2482 TRMFVHNVVTSKYFDLAIAAVIGLNVVTMAM--------EYYKMPSGLKYALKIFNYFFTAVFIL 2538
            |:|::..::....|.|.:|.::..|.:|:|:        ::|::.|.:       :.....:.|.
  Rat    57 TQMYIKQLLRHPAFQLLLAFLLVTNAITIALRTNSYLGQKHYELFSTI-------DDIVLTILIC 114

  Fly  2539 EANMKLVALGWK----LYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRV-MRVL 2598
            |     |.|||.    ::.||.||.|:..||.:..:|..:::|          |.|.|.. :|.|
  Rat   115 E-----VLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQL----------NETFITYPLRAL 164

  Fly  2599 RIARVLKLLK-MANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQG 2662
            |:..|...:: :|..||.:|    |::|.:.|:..|......:|:..||.|||..     :|
  Rat   165 RLVHVCMAVEPLARIIRVIL----QSMPDLANVMALILFFMLVFSVFGVTLFGAF-----VP--- 217

  Fly  2663 LGEHAHFANFGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLM 2727
                .||.|.|:|..|||...|.|.|..|..|...:..:.|.:         |...|:|.||:.:
  Rat   218 ----KHFQNMGVALYTLFICITQDGWLDIYMDFQVEEREYAME---------VGGAIYFAIFITL 269

  Fly  2728 AQFVLVNVVVAVLMKHLEESHKQMEDELDME-VELERELVREQEFAQEQKLCQQLAEAQSKAAAP 2791
            ..|:.:|:.|.|:..:||:..|..|:|..:: :....:...|:::..|..|.......:..:|.|
  Rat   270 GAFIGLNLFVVVVTTNLEQMMKTGEEEGHLQPITFNEKDAEEEDWTDELPLVHCTEARKETSAVP 334

  Fly  2792 PRPL 2795
            ..||
  Rat   335 QEPL 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921
		Ion_trans	2192..2448	CDD:278921
		Ion_trans	2510..2728	CDD:278921	59/231 (26%)
Catsper4	XP_342942.5	Ion_trans	91..289	CDD:278921	64/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810