Protein Alignment Ca-alpha1T and Tpcn2

DIOPT Version :9

• Sequence 1: NP_001259267.1
• Gene: Ca-alpha1T / 31550
• FlyBaseID: FBgn0264386
• Length: 3218
• Species: Drosophila melanogaster
• Sequence 2: XP_038935131.1
• Gene: Tpcn2 / 309139
• RGDID: 1311779
• Length: 867
• Species: Rattus norvegicus
• Alignment Length: 934
• Identity: 162/934 - (17%)
• Similarity: 317/934 - (33%)
• Gaps: 368/934 - (39%)

  Fly  2126 GGGERYS--KLKMLIEQLTPKHFTTEREDYSLYIFPEDN-RFRQI-------CTWFVNQKW-FDN 2179
            |||:.:|  ..::.|:|..              :|.||. ::|.|       ..|.  .:| :.|
  Rat    14 GGGQAHSGADQELCIDQAV--------------VFIEDAIKYRSIYHRLDAGSLWL--YRWYYSN 62

  Fly  2180 V--------VLLFIALNCITLA-----------MERPNIPPSS-TERLFLATANYVFTVVFTVEM 2224
            |        :.|.:||..:.:.           ..:|..||.. ||     |...:..:||..::
  Rat    63 VCQRVLGFTIFLILALAFVEVPSSFTRTADVRYRSQPWQPPCGLTE-----TIEALCLLVFLADL 122

  Fly  2225 FIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSL---ISESSPRIFGILRVFRLLRSLR 2286
            .:|    |...|......:.|.:....::.:|::|.::||   ..||       |||.||   ||
  Rat   123 SVK----GYLVGQAQLQQNLWLLAYFVVLVVSVVDWIVSLSLNCEES-------LRVRRL---LR 173

  Fly  2287 PLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQLFKGTFYYCEGENIKGVRNA 2351
            |..::..:..:|..::.:..||..:.::.|:......:|.::|:.||.             :...
  Rat   174 PFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLTIHLCLFTVIGMLLFT-------------IAEK 225

  Fly  2352 DECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRDGWVNIMYTGLDAVGVDQQPIVNYNEWRLLY 2416
            ||.:.      ..|...|.:|.:||.||.||.:.....::|.           |....|....|:
  Rat   226 DEAQN------KERLTYFRNLPEALTSLLVLLTTSNNPDVMI-----------PAYTQNRAYALF 273

  Fly  2417 FIAFILLVGFFVLNM-----------------------------------------------FVG 2434
            ||.|.|:...|::|:                                               .||
  Rat   274 FIIFTLIGSLFLMNLLTAIIYNQFRGYLMKSLQTSLFRRRLGARAAYEVLTLQAGPNGTTSELVG 338

  Fly  2435 VVVENFHRCREEQEKEEKIRRAAKRAL----------------------QMEK--KRRRMHEPPY 2475
            |..|||.|..::.:    :.:..|:|:                      :::|  .:.|..:|.|
  Rat   339 VNPENFLRVLQKTQ----LNKIHKQAIIQKVHSYEGRPILADEFQKLFDEVDKGIVKERPPKPQY 399

  Fly  2476 YTNYSPTRMFVHNVVTSKYFD-----LAIAAVI-------GLNVVTMAME-----------YYKM 2517
            .:.:..|..|   :.:.:|||     :|:..::       ||.......|           :..:
  Rat   400 QSPFLQTAQF---IFSHRYFDYLGNLIALGNLLSICVPGAGLKPAAWGTERLCPGDSQLHFHLVL 461

  Fly  2518 PSGLKY--------ALKI----------------FNYFFTA-VFILEANMKLVALG----W---- 2549
            |:|...        .|.:                |..|::. |.|....|:|.:.|    |
  Rat   462 PAGAAVQGVRAGPTGLPVLPQQRVRWPPDHHPAGFGDFYSGRVPIAAPRMELSSAGLPRSWALTT 526

  Fly  2550 ----KLY-LKDR----------------WNQL-------DVGIVLLSI---------VGIVLEE- 2576
                ||: ..:|                | ||       .|.:.:||:         |.:|:..
  Rat   527 ISAFKLWGCSERCGPGCGRCGCDCGRYDW-QLGALAVLGSVAMTVLSVAVAVLGGMMVAVVMAAW 590

  Fly  2577 --------LETNTH-----------------------QIIP-INPTII----------------- 2592
                    |.:.:|                       .:.| .:|.::
  Rat   591 ALGMSRVWLGSVSHLLGAFSAWCPYSDYCCLVTPAASSLSPSASPNLVTRLRYLLRKPEQYGPLS 655

  Fly  2593 -----RVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF--- 2649
                 |::.:|.:.|.|:::........:..|::..:..:...|.:..:::::||.:|:.||
  Rat   656 LWDMTRLVNILIVIRFLRIIPSIKPTAVVASTILGLIQNLRAFGGILVVVYYVFAMIGINLFRGV 720

  Fly  2650 -------GRLECSDEIPCQGLGEHAHFAN----FGMAFLTLFRVATGDNWNGIMKDTLRDNCDDA 2703
                   ..:..:...||....:..::.|    |..|.:||:.|...:||..|::....
  Rat   721 IVPPGNSSLVPDNSSAPCGSFEQLGYWPNNFDDFAAALITLWDVMVVNNWQVILEAYKH------ 779

  Fly  2704 ADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHL-----EESHKQM-----EDELDME 2758
                    .|...:.::||::.|::..:.:|:.:|:|:::.     .:.|||:     :...:|.
  Rat   780 --------YSGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQITYEMS 836

  Fly  2759 VELE-RELVREQEFAQEQKLCQQL 2781
            |||. |:::.|   .:|::|.::|
  Rat   837 VELMFRDILEE---PKEEELMEKL 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921
		Ion_trans	2192..2448	CDD:278921	62/317 (20%)
		Ion_trans	2510..2728	CDD:278921	53/367 (14%)
Tpcn2	XP_038935131.1	Ion_trans	66..297	CDD:395416	58/279 (21%)
		Ion_trans	<661..812	CDD:395416	29/164 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810