DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ca-alpha1T and Catsper3

DIOPT Version :9

Sequence 1:	NP_001259267.1	Gene:	Ca-alpha1T / 31550	FlyBaseID:	FBgn0264386	Length:	3218	Species:	Drosophila melanogaster
Sequence 2:	XP_006253634.1	Gene:	Catsper3 / 290989	RGDID:	1305700	Length:	395	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	82/300 - (27%)
Similarity:	139/300 - (46%)	Gaps:	52/300 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  2485 FVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGLKY--------ALKIFNYFFTAVFILEAN 2541
            |...|..|..|.:       |.:.|:....:.:..|..|        ..:|...||.:::..|..
  Rat    42 FFRKVTKSTLFQI-------LMITTVTANSFLLVLGTNYDIHFRMFRVFEISELFFVSIYACEFL 99

  Fly  2542 MKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELETNTHQIIPINPTIIRVMRVLRIARVLKL 2606
            || |.:....|.||.:|.|||.|:::..:...|.:::.|..:.:.....|       :..|||||
  Rat   100 MK-VYVDPITYWKDGYNILDVVILVIITIPYFLRKIKGNHFEYLHFADGI-------QSLRVLKL 156

  Fly  2607 LKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELFGRLECSDEIPCQGLGEHAHFAN 2671
            :..:.|||.|:..|.:.:..|.::..|.|||.|:||.||..|||..:         .|:..::.|
  Rat   157 ISYSRGIRTLIIAVGETVYTVASVLTLLFLLMFVFAILGFCLFGNAD---------RGDLTNWGN 212

  Fly  2672 FGMAFLTLFRVATGDNWNGIMKDTLRDNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVV 2736
            ...||.|||.:||.|.|..:.::..:          |...||..    |.::|:|:|.|:.:|:.
  Rat   213 LAAAFFTLFSLATVDGWTNLQEELDK----------RKFTVSRA----FTILFILLASFIFLNMF 263

  Fly  2737 VAVLMKHLEESHKQMEDELDMEVEL----ERELV--REQE 2770
            |.|::.|.|:|.|:.|.|:.:|..|    |::::  |:|:
  Rat   264 VGVMIMHTEDSIKKFEREMTLERNLALMEEKQMILRRQQD 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921
		Ion_trans	2192..2448	CDD:278921
		Ion_trans	2510..2728	CDD:278921	60/225 (27%)
Catsper3	XP_006253634.1	Ion_trans	73..269	CDD:278921	64/226 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810