Protein Alignment Ca-alpha1T and cch1

DIOPT Version :9

• Sequence 1: NP_001259267.1
• Gene: Ca-alpha1T / 31550
• FlyBaseID: FBgn0264386
• Length: 3218
• Species: Drosophila melanogaster
• Sequence 2: NP_593894.1
• Gene: cch1 / 2542812
• PomBaseID: SPAC6F6.01
• Length: 1854
• Species: Schizosaccharomyces pombe
• Alignment Length: 1679
• Identity: 310/1679 - (18%)
• Similarity: 580/1679 - (34%)
• Gaps: 510/1679 - (30%)

  Fly  1237 IRRLVEHKYFQQGILLAILINTLSMGIEYHNQPPELTAIVETSNVVFSGIFAVEMLLKVVAEG-- 1299
            :|::..|..:...|.:.|:::.:.:.|. .:.|.:.:..::...:|...::.:|||||:...|
pombe   178 LRQIYNHPLYNIFIFVVIVLHAVLLMIR-SDDPHDKSQTIDYLIIVIGILYTLEMLLKIYLFGFL 241

  Fly  1300 --------------------PFRYIANGFNVFDGIIVILSAIEICQTFMGNGTGGGGSGLSVLRT 1344
                                ...|:.:.:|..|.:.::...|.:.          |.....:.|.
pombe   242 YDGSSSFYDFINSYTKKTPRTMSYLRHSWNRVDFVAIVALWISVI----------GKKQQGIFRL 296

  Fly  1345 FRLLRILKLVRFMPNLRRQLFVMLRTMDNVA----------VFFSLLVLFIFIFSILGM------ 1393
            |.::..|:|.|.: |:.|:...:|:::...:          .||.:::      :|||:
pombe   297 FSMIACLRLTRLL-NITRKTETILKSLKESSTPLVQVVSFNAFFGVMI------AILGVQFFKAS 354

  Fly  1394 --------------YLFGGKFC----------KFLDESGL-----ERECTCPE----IISRHPQC 1425
                          ||..|:||          .:||::|.     .|...|.|    .:..:|.
pombe   355 LNRQCVWLGDYGDQYLPTGQFCGGHWENGIKRAYLDKNGFPSNVNPRGFICAEKSVCRVVENPY- 418

  Fly  1426 ECDRKHFNNILWATVTVFQILTQEDWNVVLFNGMEKTSHWAALYFVALMTFGNYVLFNLLVAILV 1490
             .:...|:|...:...:|.|::...:..::::.|:.....:.|.|:....|....|.:|::|::.
pombe   419 -SNTVSFDNFFNSLELIFVIMSSNGFTDIMYDIMDAEYFVSCLLFIISAYFLTLWLMSLVIAVVT 482

  Fly  1491 EGF-SSERNERREREQRELVKKLREETLAENY-------------------SDGMYDESRSEADS 1535
            ..| ..:.:.:.::||:.:.|.|....|.|.|                   ....||::     |
pombe   483 SSFIDLQHSGKNQKEQKSVDKHLIRNKLCEKYLFYSNFIWISFIVAQFVTLCTQTYDQT-----S 542

  Fly  1536 STTND--SYYEVRNRWRSAEDV--------------RKLQDSVELIIEAKSNMHRQRLLQPTHDY 1584
            ||.|.  .:|...:...:||.:              |:..:.|:::: |..|:
pombe   543 STANRYLIFYACVDFLLAAEVILRFFAYLPDYRLFFRRYTNLVDIVL-AVLNL------------ 594

  Fly  1585 QINELPASSAAPSASGTSGASAPGDRERDRDRDRDRERDRDRDRERDREAGGGGKEEGAQHAKPR 1649
             :..||:....|.|.|.
pombe   595 -VTLLPSIRKNPVAFGW------------------------------------------------ 610

  Fly  1650 GGLKKTYSIKERRSEAPRLSKIRLARDPPIITTTAATPQDSPSTTLEPGMSFRQWGDMEPPSPPS 1714
                              ||...:||   |.......|.......|
pombe   611 ------------------LSIFAIAR---IYRCILLIPYTRKIAKL------------------- 635

  Fly  1715 PSLLRPPNIFTGGQRSLDEGIPSIDLIPPSPVLSHKPLNILNASQLGVGMGGGVPSTAGSSSSMH 1779
                    :|:..::.|:             ::....:.:..||...|.:...:|:...|
pombe   636 --------LFSNFKQLLN-------------LMLFLVIVLFIASLCAVRLFQDLPNDGDS----- 674

  Fly  1780 SVIIDDISKSSSSTAAATPIYVPTISSTADAQSQSHSLNDVSVGSSPGGEIPATGMSRNANTGAS 1844
                ||.:.|.::|..:. :|:..|.:       |.:..||....          .:|.|:
pombe   675 ----DDDAISFATTYESF-LYMYQILT-------SENWTDVMFAI----------QARLAH---- 713

  Fly  1845 TSGSSSSERLPLAPPPQQGSFKQRLRRGSSKKRRASALALATDDNPARRTLDNQARRTQDEEEEQ 1909
                     |.|:..|  |:|.......|:....:..:|:..         .|.|....|.:.||
pombe   714 ---------LHLSWIP--GAFFTLWFLFSNNVVLSMFIAVIQ---------VNFAPSESDLKMEQ 758

  Fly  1910 QQLNNGGDNSCLLRNSNAVVSGSSSGTKETNRLSPQNSIRRLSNTLSIGSGPVGSRRASAC---- 1970
            .::.    .:.||||.|..     ..:...|.|..:|                |||:....
pombe   759 LKMY----LARLLRNYNPF-----QASLTLNALIKRN----------------GSRKGKTVDESH 798

  Fly  1971 ---IFNSQVYQNL----NQPPK--LRPGSGQRRMSSIELAFSKTSHLNLHNLEANRKSLSYTNSK 2026
               ::...:.:..    |.|||  |:|...    :|.||                        ||
pombe   799 YEWLYEDNIIKGFLRVTNIPPKEPLKPSLD----TSPEL------------------------SK 835

  Fly  2027 MDLDKWNKSYGNLNEPDNMLQQYMEARDKRKNSI---SHYNLKKRLEEKELQQLQ---QLHQQQL 2085
            ..|.|.:.::......|:   .:.:|..||...|   ...|||  ...|::|..:   ::.|.:.
pombe   836 YSLAKLSNNFKRFVMRDD---PFSQAYFKRVIGIRWEKDMNLK--TAAKDMQAAKAFVRIKQTEF 895

  Fly  2086 LQQR---QDSFSSTTQQQQQQLQQHRLSKDQQQLAMQPHSMVPGGGERYSKLKMLIEQLTPKHFT 2147
            |:..   .|.|....       ..:|:.:..|:|.|      ||..|||..:
pombe   896 LKNHPKYNDVFWVIK-------PSNRIRRFCQRLVM------PGVNERYGGV------------- 934

  Fly  2148 TEREDYSLYIFPEDNRFRQICTWFVNQKWFDNVVLLFI--------ALNCI-TLAMERPNIPPSS 2203
               |.|                     :|...|:.:||        .:.|| |...||.::....
pombe   935 ---EPY---------------------QWVYRVIQVFIYACILTAVIIECIATPIYERDHLLNDK 975

  Fly  2204 TERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISIIDLLMSLISES 2268
            ....|:.| ...|..:||:|..||::|.|.....:||..|.||.:|..::....|:|...|.|.:
pombe   976 QHAWFVWT-EVAFATIFTIEAAIKIIADGFCITPNAYLRSTWNCIDFFVLVTLWINLYAVLTSHA 1039

  Fly  2269 SPRIFGILRVFRLLRSLRPLRVIN-RAPGLKLVVQTLLSSLRPIGNIVLICCTFFIIFGILGVQL 2332
            .     :.|.||..::||.||:|| .....::....|:|....|.:..::..|..|.|.:....:
pombe  1040 L-----LSRAFRAFKALRVLRLINLTQTSQRMFHDALISGFFKIFSAAVVSATLLIPFALWAKNV 1099

  Fly  2333 FKGTFYYCEGENIKGVRNADEC----RRIPGN-------VWTN-RKYNFDDLGKALMSLFVLSSR 2385
            |.|..|.|..:|   |.:|.:|    ...|.|       ||:| ..|:||....||::||.::|.
pombe  1100 FGGLLYSCNDDN---VLSASQCVLEYASTPNNWEVWAPRVWSNPPDYDFDRFPHALLALFEIASI 1161

  Fly  2386 DGWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENFHRCREEQEKE 2450
            :|||:||.:.:|..|.:.||..|.:....::|:.|.|:...::|.:|:.:::.|:     .:...
pombe  1162 EGWVDIMRSVMDITGFNNQPQTNASSGNAMFFVLFNLVSMIYILTLFIAIIISNY-----AERTG 1221

  Fly  2451 EKIRRAAKRA-LQMEKKRRRMHEPPYYTNYSPTRM------FV---HNVVTSKYFDLAIAAVIGL 2505
            .....|.:|| |::.:|.:.| .|.......|..:      |.   |.:....:..|.|..::.|
pombe  1222 SAFFTAEQRAWLELRRKIKSM-RPSKRPAIRPLGLRGLCYDFAVQKHGIWRRTFTGLYIVHLLFL 1285

  Fly  2506 NVVTMAMEYYKMPSGLKYALKIFNYFFTAVFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIV 2570
            ..:     :|..|....|.........:..:.:...:|:..|.:..:....||..||.:.|.|:.
pombe  1286 LTI-----FYPCPIAYTYVRNSIFLILSICYTINICVKVYGLSFYYFFHSFWNMFDVVVTLGSLT 1345

  Fly  2571 G--IVLEELETNTHQIIPINPTIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLL 2633
            .  .:|.:.|         |.::..:...|.:...:.|:...:....|..||:.:||.:.:|...
pombe  1346 CNIAILAKFE---------NRSLTLLQTTLLVLVTVHLIPKFDNFDQLSKTVVASLPSIFSLIAT 1401

  Fly  2634 FFLLFFIFAALGVELFGRLECSDEIPCQGL--GEHAHFANFGMAFLTLFRVATGDNWNGIMKD-T 2695
            :.:|:..||....::||..:.       ||  |.:.:|.:...|.:.||.:..|:.||.:|.| |
pombe  1402 WIVLYITFAIAFNQIFGLTKL-------GLNGGPNKNFRSIRNALVLLFTMTFGEGWNDVMHDYT 1459

  Fly  2696 LR-DNCDDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHLEESH 2748
            :. .||.:..|...:.|.:...|...|:.:.:::.::.||:.:.|:..:....|
pombe  1460 ISYPNCVNGDDFYNSDCGNKPWAYGLFIAWNIISMYIFVNMFITVVFDNFSYIH 1513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921	51/305 (17%)
		Ion_trans	2192..2448	CDD:278921	74/268 (28%)
		Ion_trans	2510..2728	CDD:278921	46/223 (21%)
cch1	NP_593894.1	Ion_trans	201..485	CDD:278921	50/303 (17%)
		Ion_trans	533..748	CDD:278921	51/393 (13%)
		Ion_trans	968..1220	CDD:278921	73/265 (28%)
		Ion_trans	1289..1517	CDD:278921	50/241 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	114	1.000	Domainoid score	I1537
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810