Protein Alignment Ca-alpha1T and Tpcn2

DIOPT Version :9

• Sequence 1: NP_001259267.1
• Gene: Ca-alpha1T / 31550
• FlyBaseID: FBgn0264386
• Length: 3218
• Species: Drosophila melanogaster
• Sequence 2: XP_006508676.1
• Gene: Tpcn2 / 233979
• MGIID: 2385297
• Length: 769
• Species: Mus musculus
• Alignment Length: 803
• Identity: 152/803 - (18%)
• Similarity: 289/803 - (35%)
• Gaps: 256/803 - (31%)

  Fly  2157 IFPEDN-RFRQI-------CTWFVNQKW-FDNV---VLLFIALNCITLAM--------------- 2194
            :|.||. ::|.|       ..|.  .:| :.||   ||.||....:.||.
Mouse    35 VFIEDAIKYRSIYHRMDAGSLWL--YRWYYSNVCQRVLGFIIFLILILAFVEVPSSFTKTADVRY 97

  Fly  2195 -ERPNIPPSS-TERLFLATANYVFTVVFTVEMFIKVVATGMFYGHDAYFTSGWNIMDGSLVTISI 2257
             .:|..||.. ||     |......:.|.|::.:|    |...|......:.|.:....::.:|:
Mouse    98 RSQPWQPPCGLTE-----TIEAFCLLAFLVDLSVK----GYLVGQAQLQQNLWLLAYFMVLVVSV 153

  Fly  2258 IDLLMSL-ISESSPRIFGILRVFRLLRSLRPLRVINRAPGLKLVVQTLLSSLRPIGNIVLICCTF 2321
            :|.::|| ::...|        .|:.|.|||..::..:..:|..::.:..||..:.::.|:....
Mouse   154 VDWIVSLSLACEEP--------LRMRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIH 210

  Fly  2322 FIIFGILGVQLFKGTFYYCEGENIKGVRNADECRRIPGNVWTNRKYNFDDLGKALMSLFVLSSRD 2386
            ..:|.|:|:.||.             :...||.:.      ..|...|.:|.:||.||.||.:..
Mouse   211 LCLFTIIGMLLFT-------------IGEKDEAQD------QERLAYFRNLPEALTSLLVLLTTS 256

  Fly  2387 GWVNIMYTGLDAVGVDQQPIVNYNEWRLLYFIAFILLVGFFVLNMFVGVVVENF----------- 2440
            ...::|.           |....|....|:||.|.|:...|::|:...::...|
Mouse   257 NNPDVMI-----------PAYTQNRAFALFFIVFTLIGSLFLMNLLTAIIYNQFRGYLMKSLQTS 310

  Fly  2441 -------------------------------------------------------------HRCR 2444
                                                                         |.|.
Mouse   311 LFRRRLGARAAYEVLASRAGPAGTTPEFPCWPAPDWIFHRELYGLPSPQCFHYPVCSFLLAHLCL 375

  Fly  2445 EEQEKEE---------KIRRAAKRALQMEK-------------------------KRRRMHEPPY 2475
            ......|         ::.:..|:|: |:|                         .:.|..:|.|
Mouse   376 RVGVNPETFLPVLQKTQLNKTHKQAI-MQKVQSYEGRPMLADEFQKLFDEVDKGLAKERPLKPQY 439

  Fly  2476 YTNYSPTRMFVHNVVTSKYFDLAIAAVIGLNVVTMAMEYYKMPSGL------KYALKIFNYFFTA 2534
            .:.:..|..|   :.:..|||. :..::.|..:.....:..:.|.|      .:.|.|.:|.|..
Mouse   440 QSPFLQTAQF---IFSHHYFDY-LGNLVALGNLLSICVFLVLDSDLLPGERDDFVLGILDYIFIL 500

  Fly  2535 VFILEANMKLVALGWKLYLKDRWNQLDVGIVLLSIVGIVLEELET-----------NTHQIIPIN 2588
            .::||...|:.|||...||....|..|   .||:|: :::.|:.|           ...|..|::
Mouse   501 YYLLELLFKVFALGLPGYLSYHSNVFD---GLLTII-LLVSEICTLAVYRLPHSGWKPEQYGPLS 561

  Fly  2589 P-TIIRVMRVLRIARVLKLLKMANGIRALLDTVMQALPQVGNLGLLFFLLFFIFAALGVELF--- 2649
            . .:.|:|..|.:.|.|:::.....:..:.:|::..:|.:...|.:..:.:::||.:|:.||
Mouse   562 LWDMTRLMNTLIVFRFLRIIPNIKPMAEVANTILGLIPNLRAFGGILVVAYYVFAMIGINLFRGV 626

  Fly  2650 ----GRLECSDEIP------CQGLGEHAHFAN----FGMAFLTLFRVATGDNWNGIMKDTLRDNC 2700
                |.   |..:|      |....:..::.|    |..|.:||:.|...:||..|::...|
Mouse   627 IVPPGN---SSLVPDNNSAVCGSFEQLGYWPNNFDDFAAALITLWNVMVVNNWQVILEAYKR--- 685

  Fly  2701 DDAADCVRNCCVSSVIAPIFFVIFVLMAQFVLVNVVVAVLMKHL-----EESHKQ-MEDELDMEV 2759
                       .:...:.::||::.|::..:.:|:.:|:|:::.     .:.||| :.....|.|
Mouse   686 -----------YAGPWSMVYFVLWWLVSSVIWINLFLALLLENFLHRWDPQGHKQLLVGTKQMSV 739

  Fly  2760 ELE-RELVREQEFAQEQKLCQQL 2781
            ||. |:::.|   .:|::|.::|
Mouse   740 ELMFRDILEE---PKEEELMEKL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-alpha1T	NP_001259267.1	Ion_trans	332..636	CDD:278921
		Ion_trans	1261..1495	CDD:278921
		Ion_trans	2192..2448	CDD:278921	57/345 (17%)
		Ion_trans	2510..2728	CDD:278921	53/252 (21%)
Tpcn2	XP_006508676.1	Ion_trans	68..299	CDD:366146	58/277 (21%)
		Ion_trans	453..718	CDD:366146	60/286 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810