Protein Alignment Nep1 and Nepl19

DIOPT Version :10

• Sequence 1: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 181/747 - (24%)
• Similarity: 325/747 - (43%)
• Gaps: 140/747 - (18%)

  Fly   140 RCHLYRLEPDNDDRPNGR---WNQDSGSAHEGQDNICMTQECVR--TAASLLSAMDLNSDPCEDF 199
            |.||...:|..|.|...|   .:|.:.||:        .|..:|  .:|.:.|.|..::|.||:|
  Fly    23 RGHLLTGQPAIDLRIQAREQLISQSNDSAY--------VQRLMRLSKSAEMRSYMQQDADACENF 79

  Fly   200 FQYACGTWNKMHP----IPEDRSSIS-TFEVLSDQQQVILRAVLEEPID-ERDNKATIKAKTFFK 258
            :.|:||.|.:::|    .|.:.:.:. ..:..|.:||    .::|:|.: |.|..|.::.|.|:.
  Fly    80 YDYSCGNWPQINPANDAYPRETNFVQLLLKAYSHKQQ----RLMEQPANVETDEVAVLRLKEFYA 140

  Fly   259 SCMDIPQI-RKIGTGRLKQVLQSLGGWPVIE---RNWSPPADLSVERLMGQLRLNYSEPVMIELY 319
            ||:...|: ..:...:|::::...|..||:.   :.| |..:......:.:::..|...:::...
  Fly   141 SCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEW-PAEEFDWLDTVARIKRQYGFDILLLFQ 204

  Fly   320 VGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKV 384
            ..||.       :.:.|.:..||         .||.:.........:...||.||..|.....::
  Fly   205 QSADR-------IYVGQPKQILP---------EANRKAVAEDIANHLERHLGVDPKVAVTTAREI 253

  Fly   385 VLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYG 449
            ..||.::..:.:   ||...  |..|:..|...:.|...:..::::..|..  .|..:|.|..:.
  Fly   254 TEFEQKIAAIMV---DRRVG--VMSKLYTPSDADYVDVSKLTQFVETVLDR--ELLANESLYQHV 311

  Fly   450 LHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVE 514
            ..||.::.:::..|...|:.||:.    ..|:.|...|.....||                |||.
  Fly   312 PDYLMKIDELVTETPPHVLANYVF----NELLKHFYYERAESVVE----------------QCVS 356

  Fly   515 WTNKKLGVAVGALFIRDNFNQESKEVALEMIHTI----RAAFNELLAEN--DWMDDETRAVAKEK 573
            ......|..:..:.    |.|...|..|:.|:.:    :.:|..:|..:  :|:..|||....|:
  Fly   357 RVRDLFGELLDHML----FEQYEDEGTLKDIYVVWQQLQRSFRGVLQNSSANWLVPETREQLLEQ 417

  Fly   574 ADSMNERI-GYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTT 637
            .::.:..| ||.|:  |.|   |.|..|.:.|.::::|:.:||..:|   ||:        |..|
  Fly   418 LNTTSLVINGYAEV--NFT---QRYEELHLKPRDYLHNLRTILNHQS---LRV--------KVKT 466

  Fly   638 EPAVVNAFYNPNKNDIVFPAGILQPLF-YSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEG 701
            :.:|.   |:|....::.|..:|||.| :|:::||::.||.:|.::..::.|..:|..:
  Fly   467 QTSVT---YDPVGKRVLLPVALLQPNFLWSRYYPKAVRYGSLGTLLAQQLAHSLEDASK------ 522

  Fly   702 NMMQWWNNATIEAFRERTQCVIDQYSRYKIN-----EVDMFMDGRMTQGENIADNGGLKQAFRAY 761
                 |:..:...:.:|..|..:||.|.::|     |.|:       |.||||||..::.|:.||
  Fly   523 -----WDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDL-------QAENIADNLAIQVAYHAY 575

  Fly   762 KKW-----ETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSA----VHSPGFVR 817
            ::.     .:..|.| .||.||:...:||||::||:||     .||..:.|..    :.:|..:|
  Fly   576 RRLLAELDPSFLGSE-SLPQLNLGSRRLFFLSFAQLWC-----NDANEQFRDKQSLFLGTPNALR 634

  Fly   818 VLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            |||.|||.|.|...:.|...|.|...:||.::
  Fly   635 VLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_511056.2	M13	194..847	CDD:341056	165/684 (24%)
Nepl19	NP_651644.1	M13	73..664	CDD:341056	165/685 (24%)