Protein Alignment Nep1 and Nepl15

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 726
• Identity: 186/726 - (25%)
• Similarity: 316/726 - (43%)
• Gaps: 139/726 - (19%)

  Fly   182 AASLLSAM-DLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRA---VLEEPI 242
            ||.:.:.| |.....|.:|:.|||..|.::||.   |.|.:....|.:.|::.:|.   :|:...
  Fly    42 AAHIKAYMGDEKEQACNNFYNYACANWPRLHPA---RKSKTRTNYLEELQELYIRKSADMLKSAT 103

  Fly   243 DERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVI--------ERNWSPPADLSV 299
            ...:|.|..:.|.|:.||.......:.....|:.|....||||.|        |.:|.
  Fly   104 RGAENSADRQLKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEIRVASWYQYEYDWL------- 161

  Fly   300 ERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRAYHRYMT 364
             :::..|:......:.|.|.|..|.|...::.|::...|:.: ||.:||.......|..|.|.:.
  Fly   162 -QVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPM-SRRHYLHPHFEGTREIYERSIE 224

  Fly   365 QVALLLGADPATAAAE--LEKVVLFETQLVNVSLPEADRHDTSLVY----RKMLLPELQELVPE- 422
            ....|...:.:....:  ..:||..|.||.. .||    |:.:|..    |:....|::.....
  Fly   225 NKLKLYFPEQSEHWRQEVASQVVQIEQQLAK-GLP----HNPALTLAQTTRQRTAAEMKTAYGSY 284

  Fly   423 VQWQEYLQAALGPGIPLQ-----EDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMS 482
            |....|||......:.:.     ||         |::.:..::..|.:..:.||.:|:.:.:|..
  Fly   285 VDVTRYLQLIFNDNLYMDLYETPED---------YMSNLVDVIRETPKLQLANYTMWKALEALDI 340

  Fly   483 HMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIH- 546
            ..:...||..:               |  ||:...:.....:.:||.| |:|.      ::||:
  Fly   341 ARVPASQRADI---------------W--CVQLAQQFFPHQLESLFHR-NYNH------MQMINE 381

  Fly   547 ------TIRAAFNELLAEND---WMDDETR--AVAKEKADSMNERIGYPELLTNATELEQEYVNL 600
                  .|:..|.|.|..::   |:..|||  |:.|.:|..::.|      ..:..:|.::...|
  Fly   382 LQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFR------THDDNKLIRQMHGL 440

  Fly   601 TIVPDNFINNVLSILQWESEK-MLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQP-L 663
            .:..|.|..|::|:|||:::: :.:|:.:||.:::....|     .|...||.|..|...||. .
  Fly   441 ILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLP-----HYEIQKNRIQVPITFLQARF 500

  Fly   664 FYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYS- 727
            |:...:|..|.|..:||::..::.||||..||::|..|....||::.:..::..||||..:||:
  Fly   501 FWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAI 565

  Fly   728 --RYKINEVDMFMDGRMTQGEN-----IADNGGLKQAFRAYKKW-----ET--LHGREQQLPGLN 778
              .||         |:..|.::     :||||.|..|:|||::|     ||  ::.|| :||.|:
  Fly   566 FVEYK---------GKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRE-RLPLLD 620

  Fly   779 MTHDQLFFLNYAQIWCGSMRPE-----DALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGS 838
            ..|:|:|:|.|||::|... ||     |.|         |..:||...||||:.||:||.|....
  Fly   621 HDHNQIFYLGYAQLYCTDY-PETVERFDEL---------PEQLRVNTALSNSQQFANAYGCSREE 675

  Fly   839 TMNPAEKCSVW 849
            .:|...||:::
  Fly   676 KLNARFKCTLY 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	181/709 (26%)
Nepl15	NP_651098.2	M13	57..684	CDD:189000	181/707 (26%)
		PepO	57..677	CDD:226118	179/700 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850