Protein Alignment Nep1 and Nepl13

DIOPT Version :10

• Sequence 1: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 193/774 - (24%)
• Similarity: 320/774 - (41%)
• Gaps: 154/774 - (19%)

  Fly   160 QDSGSAHEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFE 224
            |.||:..:.::...:.|   :.|..:...|:|::|||.|||:||||.|.:.|........:||.:
  Fly    38 QMSGNFPDSREEQLVRQ---KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQ 99

  Fly   225 VL-----SDQQQVILRAVLEEPIDERDNK-----ATI----KAKTFFKSCMDIPQIRKIGTGRLK 275
            .|     |:|    |:.:|.:|:..:.:.     |::    |.:.|::||:.:..........|.
  Fly   100 QLMETKISEQ----LQQLLTQPLPPQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLM 160

  Fly   276 QVLQSLGGW-PVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQY 339
            ::|:..||. .|...||.  .:....:.:|:||.||...:::.|.:..:.:....|.:...:.:.
  Fly   161 KILKDNGGLRNVPNSNWQ--HNRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKL 223

  Fly   340 ---------ALPSRDYYLKESSANDRRAYHRYMTQVALLL----GADPATAAAELEKVVLFETQL 391
                     ||.:|...:::      ..|.....||...|    |.|...||.....::.||.:|
  Fly   224 TIIPAEHCNALATRGAQVRD------EVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFEL 282

  Fly   392 VNVSLPEADRHDTSLVYRKMLLPELQELVPEVQ----------WQEYLQAALGPGIPLQEDEPLV 446
            .. .:.|.|          :..|| :|..|.:|          .||.|:...| |:.|.|
  Fly   283 CK-QMGEQD----------IQKPE-EEFPPAIQAQIYGARSRTGQERLRRQKG-GMTLTE----- 329

  Fly   447 TYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEF----RKILMG------ 501
                 ..:|||.   |.|.:::...:|.....|.:.....||.:..|..    .:|.:|
  Fly   330 -----LTSEMGN---HLDFKMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYV 386

  Fly   502 -----------IQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNEL 555
                       ..|:|.|  |||:.|.:.....:|.:|.|......:|       |.:.|.||::
  Fly   387 ALNELNQPPEEAPSQRAR--QCVQVTQRLFPQVLGEMFQRHVQRDNAK-------HDLDAVFNDV 442

  Fly   556 ---LAEN---DWMDDETRAVAKEKADSMNERIGYPELLT-NATELEQEYVNLTIVPDNFINNVLS 613
               |.|.   :|||:..|..|:.:....  |:..|:..: :.|:|:.:      ..:::...:..
  Fly   443 IKALEEQFHVEWMDENDRRAARTRLSQY--RVSLPDYQSLDLTDLQFQ------KSEDYWRRLEI 499

  Fly   614 ILQWESEKMLRLLR-----QPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSL 673
            .|::.|.:....||     |..|    ..:...|.|..:|.:..::...|:||..:|:.::||||
  Fly   500 ALKYRSHQQFEALRGNDFGQDAD----GLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSL 560

  Fly   674 NYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFM 738
            .|..:|..:...:...|||:|  ::........||..|:..:|..::|...|||.|..||...|.
  Fly   561 KYALLGHRLASALVQAFDDEG--WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFR 623

  Fly   739 DGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQ------------LPGLNMTHDQLFFLNYAQ 791
            :....: |.|||..||..||.||..|     .|||            |..||.|:.||||:.:||
  Fly   624 NATRLR-EIIADGSGLNLAFNAYLAW-----LEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQ 682

  Fly   792 IWCGSMRPEDA-LTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            ..|.:...:|| |..:....|:|....|.||||||.:|...:.|.||:.||..:||.|:
  Fly   683 TRCWAKDNQDAILDSMPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_511056.2	M13	194..847	CDD:341056	184/736 (25%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	183/736 (25%)