Protein Alignment Nep1 and Nepl11

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 736
• Identity: 139/736 - (18%)
• Similarity: 258/736 - (35%)
• Gaps: 207/736 - (28%)

  Fly   162 SGSAHEGQDNICMTQ-ECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEV 225
            :|.|: |||::...: |.:..:.:|...:|.:..||:||:.|.|.     |......:....|:.
  Fly    12 AGIAY-GQDDLLRVETELLSFSHNLEPYLDTSKQPCQDFYGYVCS-----HSANLSETGRQRFQS 70

  Fly   226 LSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTG--RLK--QVLQSLGGWPV 286
            |..:..|.....:|           ::...|||||       :.|.|  .||  |:.:..||||.
  Fly    71 LLKETDVAQLMDME-----------LQLINFFKSC-------ESGRGVEALKGSQLYRQSGGWPS 117

  Fly   287 IERNWSPPADLS--VERLMGQLRL--NYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYY 347
            :|.|....:..:  .:|.:|.|..  ....|...|..| ....|..:.:||.|
  Fly   118 LEPNKVNASQRTNQTQRWLGLLGYFHEVGAPYFFETSV-TMQSNKRLVVLQPD------------ 169

  Fly   348 LKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYR--- 409
              .:..|..|.:.:.:.:|....|.:.:.|.....:|:..|..  ...:.:||..:..:.:.
  Fly   170 --GTRRNTLRKFEQRVGEVLQSFGIEQSRAHVTALEVLSLERS--RRDIVKADHVEDQVQFSYGN 230

  Fly   410 -KMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYML 473
             |.::.....|: .:.|..|.:..||...| |..:.:|...|..|.|...:|.:|....:.|::.
  Fly   231 FKRIVFGNASLI-RLDWDGYFRKLLGGKTP-QASDTIVVKQLPRLVEYFALLQNTSMVRLLNWIW 293

  Fly   474 WRLVM----------------SLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGV 522
            ...:|                .|.:|::......|||..::          :|:..:....:||
  Fly   294 TDYLMDIVDADCHQLSETYAGDLYAHVVQRVTANRVELAQM----------YSELGKAYTDQLG- 347

  Fly   523 AVGALFIRDNFNQESKEVALEMIHT-------IRAAFNELLAENDWMDDETRAVAKEKADSMNER 580
              |:::|.:...|.|::....::||       :.||::.:|
  Fly   348 --GSVWIDEISRQSSRQFLGNIMHTTLNGDERLDAAYHSIL------------------------ 386

  Fly   581 IGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDK-EKWTTEPAVVNA 644
            :|...|..|..:|.                       :.::..||......: .::....|.|||
  Fly   387 LGRRSLYRNLEKLR-----------------------KFQRTRRLASHSAQQVRRYAQMFAPVNA 428

  Fly   645 FYNPNKNDIVFPAGILQPLFYSQH-FPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWN 708
                               |..|| ....|||    :::|...:......|.....:|   .|.:
  Fly   429 -------------------FLGQHNLSTPLNY----LLLGEFFSRSLVAAGSSSRTQG---AWRS 467

  Fly   709 NATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKW-ETLHGREQ 772
            :.:...|....|||..|     .|.:|:.: ..:.|          :||..||.:| .|..|..:
  Fly   468 SDSERRFAIFQQCVGKQ-----TNAIDLLL-SLLAQ----------RQALSAYGQWLATQAGLVE 516

  Fly   773 QLPGL------NMTHDQLFFLNYAQIWC----GSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRD 827
            ::..:      .|:..:|||:....:.|    |:::.:    :.|...|:        .|.||.:
  Fly   517 RVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQQD----RKRQVTHA--------TLRNSPE 569

  Fly   828 FASAYKCPLGSTMNPA-EKCS 847
            |..|::|..|..:.|. ::|:
  Fly   570 FLEAFRCRPGDVLYPQDQRCN 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	130/701 (19%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	130/699 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910