Protein Alignment Nep1 and Nepl10

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 751
• Identity: 169/751 - (22%)
• Similarity: 271/751 - (36%)
• Gaps: 237/751 - (31%)

  Fly   179 VRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPID 243
            |.|:..:.:.::..:.||.:|:.:|||.::..      ...:..||.:.||....:...:|..:.
  Fly    26 VATSNDIHNNLNRTTSPCTNFWNFACGRFSSA------SKYVDNFERVEDQFATAMVEFMESHLG 84

  Fly   244 ERDNKA--TIK-AKTFFKSCMDIPQIRKI-GTGRLKQVLQ------------SLGG--------- 283
            |.|..|  .|| .:.::|:|.:  ..||: |..|.::::.            .|.|
  Fly    85 ENDTLAPRLIKQMRQYYKACKE--DTRKLHGNPRPEELVNQWILHPKKFLVYGLNGVFIDERVDV 147

  Fly   284 -------WPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQ-MDQLQYA 340
                   | ||:.....|||...:|.:.||         :.||..|......|.::: |.|||
  Fly   148 AANDSMRW-VIQLRMPDPADRYSDRRVLQL---------MRLYEEAWYSMGVVKLVEKMHQLQ-- 200

  Fly   341 LPSRDYYLKESSANDRRAYHRYMTQVALLLGADPATAAAELEKVV----LFETQLVNVSLPEADR 401
                |.|        |..|....|           .:.:||.:.:    .|..:|:.|:..|
  Fly   201 ----DKY--------RAEYPVVYT-----------WSFSELRQEIPIPHSFFIELLGVNHTE--- 239

  Fly   402 HDTSLVYRKMLLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRR 466
                         ||..|..||...|||:..
  Fly   240 -------------ELYHLTFEVSDVEYLREC---------------------------------- 257

  Fly   467 VVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQ-CVEWTNKKLGVAVGALFIR 530
                   :|.:....|...|.|.|.|   :.:|:.....|.|..: |:.  :.:..:.:|..:|.
  Fly   258 -------FRCLRDFASEPKDTYIRAR---QYVLVEESEPRERNPRSCIH--HMRAYLPLGMNYIY 310

  Fly   531 DNF----NQESKEVALEMIHTIRAAFNELLAEND-WMDDETRAVAKEKADSMNERIG------YP 584
            |.|    .:|.....||::.|::|||.:.|..|. .:.....|..:.|.:.:..:||      .|
  Fly   311 DRFIYQNREEDTSKVLEILSTLKAAFGQYLDANRLQLTPNQLAYVRAKLEGIQIKIGNLPEEKSP 375

  Fly   585 ELLTNATELEQEYVNLTIVPDNFINNVL------------SILQWESEKMLRLLRQPVDKEKWTT 637
            |...|      .|.:......||:.|:|            .:|...|...||......:..|..|
  Fly   376 EFYNN------HYGSANFSATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKART 434

  Fly   638 EPAVVNAFYNPNKNDIVFPAGILQ-PLF-YSQH--FPKSLNYGGIGVVIGHEITHGFDDKGRQFD 698
            .|     ||...:|.|..|...|| ||| :.:|  |..||    :|.|:|||:.|.|:.:|..||
  Fly   435 SP-----FYENERNTITVPMEFLQWPLFDHREHTIFQHSL----LGAVLGHEMNHAFEQEGILFD 490

  Fly   699 KEGNMMQWWNNATI-------EAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQ 756
            ..|      |.:.:       :.||:..:|..:|          .|:..:    |.:||..||:.
  Fly   491 AAG------NESPVGLEIRESKPFRDAIKCAEEQ----------PFVSLK----ERLADLNGLQL 535

  Fly   757 AFRAY-------KKWE-TLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSP 813
            |:.|:       :::| ..:..||:     .|..|||.|:|||.:|||:.|..|        |..
  Fly   536 AYDAFFGLAHDSRQFEYRPYAFEQE-----FTAPQLFHLSYAQFFCGSLPPVIA--------HDR 587

  Fly   814 GFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
            ...||...:.|.|.||..:.|    ..:|:..|.:|
  Fly   588 DDERVNVSVGNLRQFAYDFNC----ETSPSSVCEMW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	165/732 (23%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	163/719 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920