Protein Alignment Nep1 and Nepl9

DIOPT Version :9

• Sequence 1: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 724
• Identity: 159/724 - (21%)
• Similarity: 279/724 - (38%)
• Gaps: 210/724 - (29%)

  Fly   194 DPCEDFFQYACGTWNKMHP------IP------EDRSSISTFEVLSDQQ---QVILRAVLE-EPI 242
            |||:||:.:|||.:::...      :|      :||.:..|.||.:.:.   ::|.:...| ...
  Fly    62 DPCDDFYAHACGNFDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIPGRLISQLYTECRKR 126

  Fly   243 DERDNKATIKAKTFFKSCMD-IPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQL 306
            :||:.....:..:.::..:| ||.:     .|.|:||.|   ||.::..|..      .||.|||
  Fly   127 EERNVFTPTRLTSHWERMLDEIPFL-----ARHKEVLSS---WPFLKHQWER------RRLYGQL 177

  Fly   307 R--------LNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPS-RDYYLKESSAND--RRAYH 360
            .        ..:..|.::.:|...|    ::.:..|::|  ..|| .|:   :||.:|  ...:|
  Fly   178 NWIVLSAQLAAHGLPTLLHIYFALD----TIYVSPMEEL--PCPSIADF---QSSLSDVLEGRHH 233

  Fly   361 RYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQW 425
                ||:.::..:......|:..    |..||. ||.:..|.:||       .|..::|:.:...
  Fly   234 ----QVSRIISHEMRVLCREMRG----ELPLVR-SLSQNTRTNTS-------RPGEEQLLLDENT 282

  Fly   426 QEYLQ---AALGPGIPLQEDEPLV-----TYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMS 482
            .:|.|   |||.     ..:|.||     ...:..:|:..::|.||:.|:|:||::|:....|
  Fly   283 MDYFQQYFAALN-----FSEERLVGARKFPLDVEKITQAWEVLRHTETRIVYNYVMWQAREQL-- 340

  Fly   483 HMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALE--MI 545
             ...:..|...||.::|   .:|..:|.                 .:|.:.   |:||||.  .:
  Fly   341 -RYPDCYRVSEEFERLL---HAEYWQWH-----------------VLRRHL---SREVALASYQL 381

  Fly   546 HTIRAAFNEL----LAENDWMDDETRAVAKEKADSMNERI--GYPELLTNATELEQEYVNLTIVP 604
            ||.|  |.:|    |:..||......| :.||.:....||  .:.|...|.|||.:.|..|.:..
  Fly   382 HTTR--FQKLRRSKLSRRDWYGHLWPA-SVEKKELQVARILQNHAENYLNITELNENYEGLKLEK 443

  Fly   605 DNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNP--NKNDIVFPAGILQPLFY-- 665
            ::|..|:|            :||:          ..:.::|.:|  ::.|:..||..|:...:
  Fly   444 NSFYANLL------------ILRR----------AQLRHSFVSPYVDEEDVNQPAYFLRHFLHFV 486

  Fly   666 --SQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVID---Q 725
              |.|.|....|.          |||                      :|.:|| ::.::|   .
  Fly   487 LLSLHRPTYHYYA----------THG----------------------LELWRE-SRLLLDTDGH 518

  Fly   726 YSRYKINEVDMFM--DGRMTQGENIADNGGLKQAFRAYKKWE-TLHGREQQLPGLNMTHDQLFFL 787
            |:.....|...|.  |.::........:..:.:.|:.|:.:: :|......|.|......:.|.|
  Fly   519 YTAMDCLERQSFQHYDAKLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQGERFAFAETFVL 583

  Fly   788 NY-------------AQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGST 839
            :|             ||..|...      |:|.:|..:.|::       |..:|..|:||.....
  Fly   584 DYFGLNPHRVLFYAVAQQLCNRQ------TEIFAAQLNRGYM-------NLPEFQEAFKCGAEKA 635

  Fly   840 MNPAEKCSV 848
            |||..:|.:
  Fly   636 MNPPSRCMI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep1	NP_001284925.1	M13	194..847	CDD:189000	158/721 (22%)
Nepl9	NP_609815.1	GluZincin	62..>84	CDD:301352	8/21 (38%)
		GluZincin	<579..642	CDD:301352	18/75 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840